Flaxseed: a promising alternative for polycystic ovarian syndrome therapy

Polycystic Ovarian Syndrome (PCOS) is an endocrine disorder commonly found in females in their reproductive ages and is associated with hirsutism, obesity, menstrual irregularities, and insulin resistance. PCOS management includes the medicinal approach and with the increased incidence of PCOS, herbal approach has been increasing which includes flaxseeds and flaxseed oil but to further explore the benefits, more researches are to be conducted after which they can be included in the medical regime.

Keywords:

: Polycystic Ovarian Syndrome, flaxseed, flaxseed oil, hyperinsulinemia oxidative stress.,

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Swaroop A, Jaipuriar AS, Gupta SK, et al. Efficacy of a novel fenugreek seed extract (Trigonella foenum-graecum, Furocyst TM) in polycystic ovary syndrome (PCOS). Int J Med Sci 2015; 12: 825.
Barthelmess EK, Naz RK. Polycystic ovary syndrome: current status and future perspective. Front Biosci (Elite Ed) 2014; 6: 104.
Pilar B, Güllich A, Oliveira P, Ströher D, Piccoli J, Manfredini V. Protective role of flaxseed oil and flaxseed lignan secoisolariciresinol diglucoside against oxidative stress in rats with metabolic syndrome. J Food Sci 2017; 82: 3029-36.
Yadav K, Ghadge P, Langeh A, Kalbhare S, Phadtare P, Bhoite R. A review on herbal medicinal plant for treatment of polycystic ovarian syndrome (PCOS). AJPRD 2020; 8: 83-7.
Haidari F, Banaei-Jahromi N, Zakerkish M, Ahmadi K. The effects of flaxseed supplementation on metabolic status in women with polycystic ovary syndrome: a randomized open-labeled controlled clinical trial. Nutr J 2020; 19: 8.
Paschos GK, Yiannakouris N, Rallidis LS, et al. Apolipoprotein E genotype in dyslipidemic patients and response of blood lipids and inflammatory markers to alpha-linolenic acid. Angiology 2005; 56: 49-60.
Mirmasoumi G, Fazilati M, Foroozanfard F, et al. The effects of flaxseed oil omega-3 fatty acids supplementation on metabolic status of patients with polycystic ovary syndrome: a randomized, double-blind, placebo-controlled trial. Exp Clin Endocrinol Diabetes 2018; 126: 222-8.
Yari Z, Cheraghpour M, Hekmatdoost A. Flaxseed and/or hesperidin supplementation in metabolic syndrome: an open-labeled randomized controlled trial. Eur J Nutr. 2021; 60: 287-98.
Heidari Z, Ghasemi-Tehrani H, Fallahzadeh H, Nadjarzadeh A. The effects of flaxseed on weight loss in women with polycystic ovarian syndrome: a randomized controlled trial. Iran J Diabetes Obes 2020; 11: 79-86.