Ugurkan ERKAYIRAN, Abdullah TOK, Selim KARAKÜÇÜK, Muhammed SEYİTHANOĞLU, Tufan ARSLANCA

Evaluation of serum perlecan levels in pregnancy with mild and severe preeclampsia

Aim: To determine the levels of perlecan, which contributes to autophagy inhibition and angiogenesis, in severe and mild preeclamptic women. Material and Method: A total of 89 patients including severe preeclampsia, group 1 (n: 30), mild preeeclampsia, group 2 (n: 30) and control group, group 3 (n: 29) were included in the study. Results: All three groups were evaluated in terms of perlecan levels. Perlecan level in group 1 was determined at higher levels than other groups, and this level difference was statistically significant compared to the other two groups (p

Keywords:

Perlecan, preeclampsia, autophagy, angiogenesis, pathophysiology,

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