Dynamic Contrast Enhanced Computed Tomography in Malign-Benign Differentiation of Solitary Pulmonary Nodules The aim of this study is to evaluate the contribution of dynamic contrast enhanced computed tomography to malign-benign differentiation of solitary pulmonary nodules. Dynamic contrast enhanced computed tomography obtained at a single level was performed in 49 patients (33 malign, 16 benign) with pulmonary nodules. The difference between the highest contrast enhancement values before and after contrast material injection was calculated as the enhancement value. The correlation between mean enhancement values of malignant and benign nodules was evaluated. Statistically significant difference was found between the mean enhancement values of malign and benign nodules (p