Ali EKŞİ, F. Emre ÜSTÜN, Sezgin BİLGİN, İ. Serhat KOCAMANOĞLU, Elif BENGİ ŞENER, Binnur SARIHASAN

Sigara İçen ve İçmeyen Hastalarda Desfluran ve Sevofluranın Solunum Mekaniklerine Etkilerinin Karşılaştırılması

Bu çalışmada desfluran ve sevofluranın solunum mekaniklerine etkilerini, sigara içen ve içmeyen hasta gruplarında değerlendirmeyi amaçladık. Çalışmamıza 30-55 yaş arası, ASA I-II, akciğer hastalığı olmayan 100 hasta alındı. Sigara içen ve içmeyen gruplarda hastaların yarısında desfluran diğer yarısında sevofluran kullanılarak 25’er kişilik 4 grup oluşturuldu. Standart indüksiyon sonrası idamede O2/kuru hava karışımı içinde %6 desfluran veya %2 sevofluran uygulandı. Hastaların dinamik kompliyans (DK), hava yolu direnci (HYD cmH2O/L/sn) ve tepe hava yolu basıncı değerleri indüksiyon sonrası, entübasyondan sonraki 5., 25. dakikalar ve cerrahi sonunda kaydedildi. Gruplar arasında demografik ve hemodinamik parametreler yönünden fark bulunmadı. Desfluran grubunda sigara içmeyenlerde entübasyon sonrası 5. dk da HYD (7.36±1.18.) indüksiyon dönemine (6.56±1.08) göre yüksekken (p

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