Pericardial tamponade as the initial sign of systemic lupus erythematosus within Myasthenia Gravis Patient
Pericardial tamponade as the initial sign of systemic lupus erythematosus within Myasthenia Gravis Patient
Systemic lupus erythematosus (SLE) is an autoimmune connective tissue dis- order, mediated by numerous auto antibodies that has many different clinical manifestations and frequently affects the cardiac system. Pericarditis and peri- cardial effusion are well recognised cardiac complications. SLE is rarely re- ported with Myasthenia Gravis (MG). Myasthenia gravis (MG) is characterized by the dysfunction of neuromuscular junctions mediated the antibodies against the acetylcholine receptor and presents with weakness, fatigability of skeletal muscle. Thymectomy is a therapeutic option for patients with severe MG. Here we report a case, presented with dyspnea and revealed pericardial tamponade, pleural effusion who was diagnosed with SLE, three years after thymectomy performed for MG. Pericardial tamponade and pleural effusion are the first sign of SLE very rare and thymectomy facilitated the development of SLE.
___
- 1. Omar HA, Alzahrani MA, Al Bshabshe AA, et al. Systemic lupus erythematosus after thymectomy for myasthenia gravis:a case report and review of the literature. Clin Exp Nephrol. 2010 Jun;14(3):272-6. 2. Rada Miskovic, Aleksandra Plavsic, Aleksandra Peric-Popadic, et al. Systemic lupus erythematosusand Secondary Antiphospholipid Syndrome after Thymectomy for Myasthenia Gravis - A Case Report. Open Access Maced J Med Sci. 2015 Sep 15;3(3):439-42. 3. Mi-Jeong Park, Yun-A Kim, Shin-Seok Lee, et al. Appearance of Systemic Lupus Erythematosus in Patients with Myasthenia Gravis following Thymectomy: Two Case Reports. J Korean Med Sci 2004; 19: 134-6. 4. I Castrejón, K Shum, C-E Tseng, et al. Association between myasthaenia gravis and systemic lupus erythematosus: three case reports and review of the literature. Scand J Rheumatol 2011;40:486–490. 5. Kumar MA, Sathyamurthy I, Jayanthi K, et al. Systemic lupus erythematosus presenting as cardiac tamponade-a case report. Indian Heart J. 2012 Jan-Feb;64(1):106-7. 6. Topaloglu S, Aras D, Ergun K, et al. Systemic lupus erythematosus: an unusual cause of cardiac tamponade in a young man. Eur J Echocardiogr. 2006 Dec;7 (6):460-2.
- Yayın Aralığı: Yılda 4 Sayı
- Başlangıç: 1980
- Yayıncı: Ondokuz mayıs Üniversitesi Tıp Fakültesi