Oktay YAPICI, Meltem AYDIN, Murathan ŞAHİN

Osteoblastik Metastaz, Kan Kalsiyum ve Alkalen Fosfataz Yüksekliği Arasındaki İlişki

Tüm vücut kemik sintigrafisi (TVKS) osteoblastik metastazların tespitinde çok sensitif, fakat non-spesifik bir tanı yöntemidir. Bu retrospektif çalışmanın amacı; kemik sintigrafisinde metastaz saptanan hastalarda, kan kalsiyum (Ca) ve total alkalen fosfatazın (AP) metastaz gösterimindeki hassasiyetini değerlendirmektir. Hasta grubu olarak osteoblastik metastaz yapan en sık üç kanser; akciğer, prostat ve meme kanseri seçilmiştir. Increased plasma calcium and alkaline phosphatase level in osteoblastic metastases The bone scan is very sensitive but not spesific for the detection of osteoblastic bone metastases. The aim of this retrospective study was to evaluate the role of plasma calcium (Ca) and alkaline phosphatase (AP) level in the detection of bone metastases of the three frequently observed cancers including the lung, prostate and breast.

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