The Efficacy of Diastolic Balloon Pulsation in Coronary Sinus on Myocardial Metabolism and Haemodynamics The effect of diastolic coronary sinus balloon pulsation on acute myocardial ischemia and infarction was evaluated. A device for this purpose was developed that consisted of a balloon catheter and pump system, the produced controlled, intermittant diastolic pulsaüon in coronary sinus. It was hypotesized that; facilitate improved retrograde flow to ischemic areas and allow for more complete oxygen exchange and venous washout of metabolits, with elevated coronary sinus pressure and retrograde pulsation. For this purpose; the experimental study was done on 10 dogs. First stage; Coronary Sinus Diastolic Ballon Pulsation (CSDBP) was performed on normally myocardium, at beat to beat 1:1, 2:1, and 3:1 cardiac cycle. Any haemodynamics deteriotions were showed. Then, coronary perfusion deteriotions were performed by coronary artery ligation. In this stage; mean EKG-ST segment level elevated to 6.3±0.95 mm (p