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Does the Frequency of Ureaplasma Increase In Human Papillomavirus Positive Women?

This study aimed to investigate the positive prevalence rate of Ureaplasma in Human papillomavirus (HPV) positive women. The role of sexually transmitted diseases (STD) in developing cervical cancer is evident. Clinical consequences can be prevented by screening and identifying risk factors. This retrospective cohort study was approved by the Ethics Committee of Sisli Memorial Hospital. Ureaplasma and HPV and PAP smear tests were performed for 526 sexually active women aged between 21 and 45 years (mean 31.66±4.91 years) visiting a Sisli Memorial Hospital for routine cervical screening. The association of HPV and Ureaplasma detection with cytological results were examined. The prevalence of Ureaplasma in asymptomatic women was 31%, high-risk HPV (HR-HPV) and Ureaplasma coincidence as 56.6% and the prevalence of Ureaplasma in HR-HPV was 91.5%. Most positive HPV was observed in the age range of 26-30 (50%). The most positive Ureaplasma was observed in the age range of 26-30 (51%). The highest simultaneous occurrence of two infections was observed in the age range of 26-30 (51%). Cervical screening abnormality was observed more in Ureaplasma-positive women. There was a statistically significant association between pap smear result and Ureaplasma (p-value < 0.001). There was a statistically significant association between HPV-positive and Ureaplasma (p-value < 0.001). There was a statistically significant association between HR-HPV and Ureaplasma (p-value < 0.001). Regarding the high prevalence of Ureaplasma in HR-HPV women, screening in women, especially in the age range of 26-30 years, is a breakthrough and can prevent adverse clinical consequences.

Keywords:

human papillomavirus, ureaplasma, cervical cancer sexually transmitted disease,

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