Özlem EROĞLU KAYACIK, Ayhan Gazi KALAYCI

Karaciğer İşlev Testleri

Karaciğer protein, karbonhidrat ve yağ metabolizmasında önemli rolü olan kompleks bir organdır. Safra yapımı ve salınımından sorumludur. Aynı zamanda lipoproteinleri ve plazma proteinlerini sentezler. Glikojenez, glikojenoliz ve glikoneojenez ile normal kan glukoz düzeyini sağlar. Metabolizmanın artık ürünleri yine karaciğer tarafından zehirsizleştirilir. Anormal karaciğer enzim düzeyleri karaciğer hasarını gösterebilir. Karaciğer enzim düzeylerindeki değişiklikler klinikte en sık karşılaşılan problemlerden biridir. Karaciğer enzimlerinin patofizyolojisini bilmek değişikliklerini anlamak için önemlidir. Liver Function Tests The liver is a complex organ that has crucial role in protein, carbonhydrate and fat metabolism. It is responsible for synthesizing and secreting bile. It also synthesizes lipoproteins and plasma proteins. By glycogenesis, glycogenolysis and gluconeogenesis it maintains normal blood glucose level. Waste products of metabolism are also detoxified by liver. Abnormal liver enzyme levels may signal liver damage. Alterations in liver enzyme levels are one of the most common problems in clinical practice. Knowledge of the pathophysiology of liver enzymes is an essential guide to understanding their alteration.

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