Hasan ULUBAŞOĞLU, Sertaç BATIOĞLU, Davut GÜVEN

Twin pregnancy in a woman with hypogonadotropic hypogonadism and uterus didelphys: A case report and literature review

Hypogonadotropic hypogonadism is a rarely seen medical condition arising from absence or decrease of hypothalamic pituitary function . Hormone plasma concentrations are either can not be determined or are at very low rates. Uterus didelphys is a congenital uterine about medial fusion defects of mullerian ducts. A 22-year-old female patient applied to our clinic due to premier infertility. The diagnosis of uterus didelphys was confirmed as a result of hysterosalpingogra- phy.Recombinant FSH was started on ovulation induction. In the transvaginal ultrasonography performed 3 weeks later, 2 gestational sacs and fetal heartbeats in both cavities were observed.After cesarean operation ,strassmann procedure was performed and both cavities were combined in the same session.

Keywords:

Cesarean Hypogonadotropic hypogonadism, Infertility, Uterus didelphys,

PDF

___

Awwad, J.T., Farra, C., Mitri, F., Abdallah M.A., Jaoudeh, M.A., Ghazeeri, G, 2013. Split daily recombinant human LH dose in hypogonadotrophic hypogonadism: A nonrandomized controlled pilot study. Reprod. Biomed. 26, 88-92. doi: 10.1016/j. rbmo.2012.09.016. Epub 2012 Oct 4.
Bhattacharya, S., Mistri, P.K., 2010. Twin pregnancy in a woman with uterus didelphys. J. Health and Allied Sci. Doi: 10.1012/ jhas.1152.
Chan Y.Y., Jayaprakasan, K., Tan, A., Thornton, J.G., Coomarasamy, A., Raine-Fenning, N.J., 2011. Reproductive outcomes in women with congenital uterine anomalies: A systematic review. Ultrasound Obstet. Gynecol. 38, 371–382. Doi: 10.1002/ uog.10056.
Hsing-Tse, Y., Chyi-Long, L., Hong-Yuan, H., Yung-Kuei, S., 2012. Successful pregnancy in a woman with kallmann’s syndrome using human menopausal gonadotropin followed by low-dose human chorionic gonadotropin in the mid-to-late follicular phase. Taiwanese J. Obstet. Gyn. 2, 300-302. Doi: 10.1016/j.tjog.2012.04.027.
Lolis D.E., Pashopoulos, M., Makrydimas, G., Zikopoulos, K., Sotiriadis, A., Paraskevaidis, E., 2005. Reproductive outcome after strassman metroplasty in women with a bicornuate uterus. J. Reprod. Med. 50, 297-301. Doi: 10.1002/jrm.10056
Meiling, H., Anthony, O., George, A.,2011. Congenital uterine anomalies and a diverse pregnancy outcomes. Am. J. Obstet. Gynecol. 205, 558.
Raga, F., Bauset, C., Remohi, J., Fernando ,Bonilla-Musoles., Carlos, Simon., Antonio, Pellicer., 1997. Reproductive impact of congenital mullerian anomalies. Hum. Reprod. 122277-2281. Doi: 10.1093/humrep/12.10.2277.
Tanaka,T,. Fujimoto,S., Matsuzaki,N.,Sakuragi,N., Ichinoe,K.,1988.Twin gestation induced with hMG-hCG in a patient witha bicornuate uterus: report of a successful delivery. Int. J. Fertil. 33, 33-35. Zhang, Y., Zhao, Y., Qiao, J., 2010. Obstetric outcome of women with uterine anomalies in china. Chinese Med. J. 123, 418-422.