Covid 19 Pandemi’sinde Behçet hastalığı ve Ailesel Akdeniz Ateşi hastalığında fiziksel aktivite düzeyi, uyku, yorgunluk ve yaşam kalitesi

Amaç: Çalışmamızın birincil amacı, Behçet ve Ailesel Akdeniz Ateşi (AAA) olan hastalarda, fiziksel aktivite, uyku, yorgunluk, ağrı ve yaşam kalitesi düzeylerindeki değişimlerin karantina öncesi ve sırasındaki karşılaştırılmasıdır. İkincil amacı, Behçet ve AAA'lı hastaların Covid-19 Pandemi sırasındaki egzersiz davranışlarını belirlemektir. Yöntem: Bu kesitsel çalışmaya toplam 21 Behçet Hastası (Ortalama yaş 42 yıl, %57’si kadın) ve 21 AAA hastası (Ortalama yaş 39 yıl, %71,4’ü kadın) dahil edildi. Hastalara Uluslararası Fiziksel Aktivite Anketi- Kısa Form, Kısa Form 36 ve Egzersiz Aşamaları Değişim Anketi uygulandı. Uyku memnuniyeti, yorgunluk ve ağrı Sayısal Derecelendirme Ölçeği ile değerlendirildi. Bulgular: Başlangıçta sosyodemografik verilerde ve gruplar arasında uyku süresi dışındaki tüm sonuçlarda istatistiksel olarak anlamlı fark olmadığı bulundu (p>0,05). Fiziksel aktivite, ağrı, yorgunluk, uyku ve yaşam kalitesi hem Behçet hem de AAA hastalarında karantina öncesi ile karşılaştırıldı. Behçet hastalarında ağrı ve yorgunluk düzeyinin arttığı hem Behçet hem de AAA hastalarında ise fiziksel aktivite ve yaşam kalitesinin azaldığı bulundu (p<0,05). Behçet hastalarında fiziksel aktivite ile yaşam kalitesinin ruh sağlığı alt boyutu arasında anlamlı bir ilişki bulundu. Ayrıca çalışmamızda Behçet hastalarının sadece %9,5’i ve AAA hastalarının sadece %14,3'ü 6 aydan uzun süredir egzersiz yaptığını belirtmiştir. Sonuç: Her iki gruptaki hastalar fiziksel olarak inaktifti ve çoğunluğu egzersiz yapmıyordu. Bu durum karantina döneminde arttı. Behçet ve AAA hastalarında bu semptomlara olumlu etki yapabilmek için kişiselleştirilmiş egzersiz tedavisi planlanabilir ve fiziksel aktivite düzeyleri arttırılabilir.

Anahtar Kelimeler:

Behçet Hastalığı, Ailevi Akdeniz Ateşi, Pandemi, Fiziksel aktivite, Romatoloji

Physical activity level, sleep, fatigue and quality of life in Behçet’s Disease and Familial Mediterranean Fever Disease during the Covid 19 Pandemic

Purpose: The primary aim of our study was to compare the changes in physical activity, sleep, fatigue, pain, and quality of life levels before and during confinement in patients with Behçet’s Disease (BD) and Familial Mediterranean Fever (FMF) disease (FMFD). The secondary aim of the present study was to determine the exercise behavior of patients with BD and FMF during the Covid 19 Pandemic. Methods: A total of 21 patients with BD (mean age was 42 years, 57.1% were female) and 21 patients with FMF (Mean age was 39 years, 71.4% were female) were included in this cross sectional study. Internal Physical Activity Questionnaire- Short Form, Short Form 36 and Exercise Stages of Change Questionnaire were administered to all participants. Sleep satisfaction, fatigue and pain was assessed with the Numeric Rating Scale. Results: There were no significant differences in sociodemographic data and all outcome scores except sleep duration between the groups at baseline (p>0.05). Physical activity, pain, fatigue, sleep, and quality of life were compared with pre-confinement in both BD and FMF patients. It was found that the level of pain and fatigue increased in BD patients, and physical activity and quality of life decreased in both BD and FMF patients (p<0.05). We found a significant relationship between physical activity and mental health subscale of quality of life in BD patients (p<0.05). In addition, only 9.5% of BD patients and only 14.3% of FMFD patients in our study stated that they had been exercising for more than 6 months. Conclusion: The patients in both groups were physically inactive and the majority of them did not exercise. This situation increased during the confinement period. In order to have a positive effect on these symptoms, personalized exercise therapy can be planned and physical activity levels can be increased in BD and FMF patients.

Keywords:

behcet disease, pandemic, physical activity,

PDF

___

1. Tursen U, Gurler A, Boyvat A. Evaluation of clinical findings according to sex in 2313 Turkish patients with Behçet's disease. Int J Dermatol. 2003;42:346–351.
2. Gur A, Sarac AJ, Burkan YK, et al. Arthropathy, quality of life, depression, and anxiety in Behcet's disease: relationship between arthritis and these factors. Clin Rheumatol. 2006;25:524– 531. 3. Uygunoglu U, Benbir G, Saip S, et al. A polysomnographic and clinical study of sleep disorders in patients with Behcet and neuro- Behcet syndrome. Eur Neurol. 2014;71:115–119.
4. Bashardoust B. Familial Mediterranean fever; diagnosis, treatment, and complications. J Nephropharmacol. 2015;4:5–8.
5. Sahin S, Yalcin I, Senel S, et al. Assessment life quality of familial Mediterranean fever patients by short form-36 and its relationship with disease parameters. Eur Rev Med Pharmacol Sci. 2013;17:958–963.
6. Schwartz T, Langevitz P, Zemer D, et al. Behçet’s disease in familial Mediterranean fever: characterization of the association between the two diseases. Semin Arthritis Rheum. 2000;29:286–295.
7. Ghate JV, Jorizzo JL. Behçet’s disease and complex aphthosis. J Am Acad Dermatol. 1999;40:1–18.
8. Dikmen AU, Kına HM, Özkan S, et al. Epidemiology of COVID-19: What We Learn from Pandemic. Journal Of Biotechnology and Strategic Health Research. 2020;4:29–36.
9. T.C. Sağlık Bakanlığı. COVID-19 (SARS-CoV-2 Enfeksiyonu Rehberi) https://covid19bilgi.saglik.gov.tr/depo/rehberler/COVID-19_Rehberi.pdf. Accessed: 05.06.2020.
10. Velavan TP, Meyer CG. The COVID-19 epidemic. Trop Med Int Heal. 2020;25:278–280.
11. Lippi G, Henry BM, Sanchis-Gomar F. Physical inactivity and cardiovascular disease at the time of coronavirus disease 2019 (COVID-19). Eur J Prev Cardiol. 2020;27:906–908.
12. Ünal M, Bildik C, Apaydın Z, et al. Covid-19disease and physical inactivation. J Med Sci. 2020;1:13–19.
13. Manning VL, Hurley MV, Scott DL, et al. Are patients meeting the updated physical activity guidelines? Physical activity participation, recommendation, and preferences among innercity adults with rheumatic diseases. J Clin Rheumatol. 2012;18:399–404.
14. Huffman KM, Pieper CF, Hall KS, et al. Selfefficacy for exercise, more than disease-related factors, is associated with objectively assessed exercise time and sedentary behaviour in rheumatoid arthritis. Scand J Rheumatol. 2015;44:106–110.
15. Henchoz Y, Bastardot F, Guessous I, et al. Physical activity and energy expenditure in rheumatoid arthritis patients and matched controls. Rheumatology. 2021;51:1500–1507.
16. Ölçer G, Dağ A, Kaşlı K, et al. Physical activity and exercise in patients with rheumatism in the COVID-19 Pandemic. Türkiye Klinikleri. 2020;1:69–74.
17. Lee PH, Macfarlane DJ, Lam TH, et al. Validity of the international physical activity questionnaire short form (IPAQ-SF): A systematic review. Int J Behav Nutr Phys Act. 2011;8:115.
18. Song JE, Chae HJ, Kim CH. Changes in perceived health status, physical symtoms, and sleep satisfaction of postpartum women over time. Nursing and Health Sciences. 2014;16:335–342.
19. Nicklin J, Cramp F, Kirwan J, et al. Measuring fatigue in rheumatoid arthritis: a cross-sectional study to evaluate the Bristol Rheumatoid Arthritis Fatigue Multi-Dimensional questionnaire, visual analog scales, and numerical rating scales. Arthritis Care Res. 2010;62:1559–1568.
20. Huskisson EC. Measurement of pain. Lancet. 1974;304:1127–1131.
21. Koçyiğit H, Aydemir Ö, Ölmez N, et al. Kısa Form-36 (KF36)’nın Türkçe Versiyonunun Güvenilirliği ve Geçerliliği. İlaç ve Tedavi Dergisi. 1999;12:102–106.
22. Carr AJ, Thompson PW, Kirwan JR. Quality of life measures. Br J Rheumatol. 1996;35:275–281.
23. Henchoz Y, Zufferey P, So A. Stages of change, barriers, benefits, and preferences for exercise in RA patients: a cross- sectional study. Scand J Rheumatol. 2013;42:136–145.
24. Gümüş Y, Kitiş Y. The validity and reliability of exercise behavior change Scales. Journal of Hacettepe University Faculty of Nursing. 2015;2:1–19.
25. Zhang SX, Wang Y, Rauch A, et al. Unprecedented disruption of lives and work: health, distress and life satisfaction of working adults in China one month into the COVID-19 outbreak. Psychiatry Res. 2020;288:112958.
26. Guo YR, Cao QD, Hong ZS, et al. The origin, transmission and clinical therapies on coronavirus disease 2019 (COVID-19) outbreak -an update on the status. Mil Med Res. 2020;7:11.
27. Sveaas SH, Smedslund G, Hagen KB et al. Effect of cardiorespiratory and strength exercises on disease activity in patients with inflammatory rheumatic diseases: a systematic review and meta-analysis. Br J Sports Med. 2017;51:1065–1072.
28. Hernández-Hernández V, Ferraz-Amaro I, Díaz-González F. Influence of disease activity on the physical activity of rheumatoid arthritis patients. Rheumatology (Oxford). 2014;53:722-731.
29. Swinnen TW, Scheers T, Lefevre J, et al. Physical activity assessment in patients with axial spondyloarthritis compared to healthy controls: a technology-based approach. PLoS One. 2014;9:e85309.
30. Makay B, Kiliçaslan SK, Anik A, et al. Assessment of sleep problems in children with familial Mediterranean fever. Int J Rheum Dis. 2017;20:2106–2112.
31. Chaput JP, Dutil C, Sampasa-Kanyinga H. Sleeping hours: what is the ideal number and how does age impact this. Nat Sci Sleep. 2018;10:421–430.
32. Duruoz MT, Unal C, Bingul DK, et al. Fatigue in familial Mediterranean fever and its relations with other clinical parameters. Rheumatol Int. 2018;38:75–81.
33. Güler T, Aslan NÇ, Garip Y, et al. Disease activity in Turkish patients with Behçet's Disease: Association with fatigue, psychological status and quality of life. Turkiye Klinikleri J Med Sci. 2017;37:130–135.
34. Sandikci SC, Colak S, Omma A, et al. An evaluation of depression, anxiety and fatique in patients with Behçet’s disease. Int J Rheum Dis. 2019;22:974–979.
35. Bodur H, Borman P, Ozdemir Y, et al. Quality of life and life satisfaction in patients with Behcet's disease: relationship with disease activity. Clin Rheumatol. 2006;25:329–333.
36. Pollard LC, Choy EH Gonzalez J, et al. Fatigue in rheumatoid arthritis reflects pain, not disease activity. Rheumatology. 2006;45:885–889.
37. Nicassio PM. Psychosocial factors in arthritis. Springer, Berlin; 2016.
38. Melikoglu M, Melikoglu MA. What affects the quality of life in patients with Behçet’s disease? Acta Reumatol Port. 2014;39:46–53.
39. Ertam I, Kitapcioglu G, Aksu K, et al. Quality of life and its relation with disease severity in Behcet's disease. Clin Exp Rheumatol. 2009;27:18–S22.