Ulaş KARAOĞLU, Aydın SARIHAN, Mehtap BULUT

A Rare Case of Transdermal Methanol Intoxication

Anahtar Kelimeler:

-

A Rare Case of Transdermal Methanol Intoxication

Introduction: Methanol is a clear, colorless, and highly toxic liquid which is a common component of antifreeze solutions, paints, varnishes, gasoline mixtures, and various solvents. Even though methanol is used only in industry, when ingested accidentally or for suicide it may cause methanol intoxication which has high mortality rates. Methanol intoxication is generally seen after accidental or suicidal oral intake. Methanol can be absorbed by inhalation or through the skin, which rarely leads to clinical toxicity.Case Report: Herein, we present a case of methanol intoxication associated with absorption through the skin which is one of the rare ways of poisoning. We aim to emphasize that methanol intoxication rarely occurs after dermal exposure.Conclusion: Emergency department physicians must consider methanol intoxication in patients of high anion gap metabolic acidosis with visual symptoms even if the patient has no history of oral intake

Keywords:

Methanol intoxication, transdermal denatured alcohol,

PDF

___

Gök E, Horoz M, Turgutalp K, Kıykım AA. Fatal Transdermal Methanol Intoxication: A Case Report and Review of Literature. Turkiye Klinikleri J Med Sci 2011; 31: 234-9. [CrossRef ]
Karaduman F, Asil T, Balci K, Temizoz O, Unlu E, Yilmaz A, et al. Bilateral basal ganglionic lesions due to transdermal methanol intoxication. J Clin Neurosci 2009; 16: 1504-6. [CrossRef ]
Soysal D, Yersal Kabayegit O, Yılmaz S, Tatar E, Ozatli T, Yildiz B, et al. Transdermal methanol intoxication: a case report. Acta Anesthesiol Scand 2007; 51: 779-80. [CrossRef ]
İşcan Y, Coşkun Ç, Öner V, Türkçü FM, Taş M, Alakuş MF. Bilateral total optic atrophy due to transdermal methanol intoxication. Middle East Afr J Ophthalmol 2013; 20: 92-4. [CrossRef ]
Tokgöz OS, Güney F, Kamış Ü, Paksoy Y. Bilateral putaminal and optical involvement after low dose of methanol exposure: case report. Erciyes Med J 2012; 34: 91-4. [CrossRef ]
Liesivuori J, Savolainen H. Methanol and formic acid toxicity: biochemi- cal mechanisms. Pharmacol Toxicol 1991; 69: 157-63. [CrossRef ]
Anyfantakis D, Symvoulakis EK, Cristodoulakis EV, Frantzeskakis G. Rul- ing in the diagnosis of methanol intoxication in a young heavy drinker: a case report. J Med Life 2012; 5: 332-4.
Çelebi S, Aydemir O, Yılmaz T. Metil alkol intoksikasyonunda göz bulguları. MN Ophthalmology 2001; 8: 255-8
Mégarbane B. Treatment of patients with ethylene glycol or methanol poisoning: focus on fomepizole. Open Access Emerg Med 2010; 2: 67- 75. [CrossRef ]