İntroduction: The use of snake skin, both transdermal and orally comes from ancient Chinese medicine. People eat snake skin for skin disorders, convulsions, gallbladder disorders and hypertension. People also apply snake skin by transdermal way for skin disorders such as sores,boils, itching, psoriasis, scabies, hemorrhoids, eye infections, cloudy spots in the eye..etc. There isn’t enough reliable information available about snake skin to know if it is safe or what the side effects might be. Case: The patient described in the case report has given his informed consent for publication. We present a case of anaphylaxis developed after 10 days of snake skin eating and dicharged after 4 days treatment with full recovery. Conclusion: It must be kept in mind that natural products are not always necessarily safe and also dosages can be important. Availability of exotic foods for different uses is steadily increasing. No matter how developed we are, those who try traditional medicine methods instead of chemical drugs will always be. So we must be careful and always be awake for different food consumptions.