Unexpected fatal empyema in a previously healthy woman

Streptoccoccus pyogenes is gram + aerob coccus and it is described as group A Streptococcus (GAS) according to the Lancefield classification. GAS may cause pneumonia and pleural effusion rarely.Herein we reported a 43 years old previously healthy woman presented to the Emergency Department (ED) with the complaint of chest-back pain and shortness of breath. During her follow up she developed septic shock due to the empyema. 13rd hour of her admission, cardiopulmonary arrest developed and she died in spite of the appropriate and immediate treatment. 2 days later after her admission, streptoccoccus pyogenes was detected in her pleural effusion and blood culture. In conclusion clinicians should be aware of this potential fatal condition also in healthy patients and start the treatment immediately.

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  • 1- Muller MP, Low DE, Green KA, Simor AE, Loeb M et al. Clinical an epidemiologic features of group A streptococcal pneumonia in Ontario, Canada. Arch Intern Med 2003;163:467–72.) Arch Intern Med 2003;163:467–72
  • 2- Birch C, Gowardman J. Streptococcus pyogenes: a forgotten cause of severe community- acquired pneumonia. Anaesth Intensive Care 2000;28:87–90
  • 3- Tamayo E, Montes M, Vicente D, Pérez-Trallero E. Streptococcus pyogenes pneumonia in adults: clinical presentation and molecular characterization of isolates. 2006–2015. PLoS One 2016;11:e0152640
  • 4- Ampofo K, Herbener A, Blaschke AJ, Heyrend C, Poritz M et al. Association of 2009 pandemic influenza a (H1N1) infection and increased hospitalization with parapneumonic empyema in children in Utah. Pediatr Infect Dis J. 2010;29:905–9.
  • 5- 5- Asai N, Suematsu H, Sakanashi D, Kato H, Hagihara M et al. A severe case of Streptococcal pyogenes empyema following influenza A infection. BMC Pulmonary Medicine (2019) 19:25
  • 6- 6- Sakaia, T, Taniyamab D, Takahashia S, Nakamuraa, M, Takahashic, T. Pleural empyema and streptococcal toxic shock syndrome due to Streptococcus pyogenes in a healthy Spanish traveler in Japan. IDCases 9 (2017) 85–88