Mide Biyopsilerinde Sydney Sınıflamasına Göre Histolojik Değerlendirme ve Yaş Gruplarına Göre Kronik Gastritde Mukozal Histolojik Bulguların Karşılaştırılması

Çalışmanın amacı; kronik gastrit tanısı almış olguların biyopsi materyallerinin Sydney sistemine göre değerlendirilmesi ve değişken parametrelerin yaş gruplarında karşılaştırılmasıdır. Gastritlerde Sydney sistemi gastrik mukozada oluşan değişikliklerin beş ana histolojik özellik (kronik inflamasyon, nötrofil aktivitesi, glandüler atrofi, intestinal metaplazi ve Helikobakter pilori yoğunluğu) şeklinde derecelendirilmesidir. Çalışmamızda endoskopik biyopsi ile kronik gastrit tanısı almış 31 yaş altı 63 olgu, 31-60 yaş aralığında 177 olgu ve 61 yaş üstü 187 olgu değerlendirilmiştir. Helikobakter pilori antrum lokalizasyonunda 31-60 yaş grubunda daha fazla izlendi. Buna karşın, 31 yaş altı grubunda Helikobakter pilori infeksiyon dağılımının pangastrit şeklinde olduğu izlendi. 31 yaş altı grubunda akut inflamasyonu diğer yaş gruplarına göre anlamlı olarak yüksek tespit edildi. 61 yaş üstü grubunda atrofi görülme sıklığı yüksek saptandı. Çalışmamızda artan yaşla birlikte atrofi ve intestinal metaplazi oranının Helikobakter piloriden bağımsız arttığı tespit edildi.

Anahtar Kelimeler:

Gastrit , Sydney Sınıflaması, Yaş

Histologic Evaluation of Gastric Biopsies According to Sydney Classification and Comparison of Chronic Gastritis Mucosal Histological Findings by Age Group

The aim of this study is to evaluate the materials of gastric biopsies in cases diagnosed as chronic gastritis according to the Sydney system and to compare the parameters according to age groups. The Sydney system of gastritis has five main histological features of changes in gastric mucosa graded (chronic inflammation, neutrophil activity, glandular atrophy, intestinal metaplasia and Helicobacter pylori density) In our study, we evaluated 63 patients under 31 years, 177 patients between the ages of 31-60 and 187 patients over 61 years, who were diagnosed as having chronic gastritis by endoscopic biopsy. In 31-60 age group, the localization of Helicobacter pylori was often the antrum. In contrast, in the under 31 years of age group, Helicobacter pylori infection were found to be in the form of the distribution pangastrit. Acute inflammation in the under31 years group was found to be significantly higher than other age groups. In over 61years group, high incidence of atrophy was found. In our study, we detected the rate in atrophy and intestinal metaplasia with Helicobacter pylori is independently increased with age.

Keywords:

Gastritis, Sydney Classification, Age,

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