İlhan KURULTAK, Mustafa ALTAY, Ahmet SANLİ, Sema SECİLMİS, Refika KARAER, Murat DURANAY

Hemodiyaliz: akut izoniazid zehirlenmesinde yaşam kurtarıcı tedavi

Akut izoniazid zehirlenmesi kronik şekline nazaran oldukça nadir görülür. Genellikle tekrarlayan nöbetler, metabolik asidoz ve koma ile ortaya çıkar. Acil olarak tedavi edilmezse hayatı tehdit edebilir. Tedavisinde piridoksin kullanılır. Bu yazıda akut izoniazid zehirlenmesi nedeniyle acil servise şuuru kapalı olarak getirilen ve hemodiyaliz ile yaşama dönen 16 yaşında bayan hastamızı sunuyoruz

Anahtar Kelimeler:

akut zehirlenme, hemodiyaliz, izoniazid, metabolic asidoz, piridoksin

Hemodialysis: the life delivering therapy in a case of acute isoniazid intoxication

Acute isoniazid intoxication is rarely seen compared to chronic intoxication. It usually manifests with repetitive seizures, metabolic acidosis and coma. If it isn’t treated urgently, it can be life threatening. Pyridoxine is used to be given in treatment. In this article, we present a case of 16 years old woman who was brought to emergency service with unconsciousness because of the acute isoniazid intoxication and whose life was delivered by hemodialysis

Keywords:

acute intoxication, hemodialysis, isoniazid, metabolic acidosis, pyridoxine,

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Temmerman W, Dhondt A, Vandewoude K. Acute isoniazid intoxication: seizures, acidosis and coma. Acta Clin Belg 1999;54: 211-6.
Tai DY, Yeo JK, Eng PC, Wang YT. Intentional overdosage with isoniazid: case report and review of literature. Singapore Med J 1996;37:222-5.
Romero JA, Kuczler FJ Jr. Isoniazid overdose: recognition and management. Am Fam Physician 1998;57: 749-52.
Alvarez FG, Guntupalli KK. Isoniazid overdose: four case reports and review of the literature. Intensive Care Med 1995;21:641-4.
Okutur SK, Borlu F, Ersoy ÇY, Paksoy F. Acute Isoniazid Intoxication: Convulsion, Rhabdomyolysis and Metabolic Acidosis. Turk J Med Sci 2006;36:397-9.
Eyüboğlu T, Derinöz O. Rhabdomyolysis due to isoniazid poisoning resulting from the use of intramuscular pyridoxine. Turk J Pediatr 2013;55:328-30.

Yayın Aralığı: Yılda 6 Sayı
Başlangıç: 2011
Yayıncı: Rabia YILMAZ

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