Gadoliniumlu MRG tetkikleri ve girişimsel nöroradyolojik uygulamaların subaraknoid mesafeye kontrast madde sızıntısına etkisi

Amaç: Gadoliniumlu ve iyotlu kontrast maddelerin çeşitli patolojilerde subaraknoid mesafeye (SAM) geçtiği, hemorajiyi taklit ettiği ve nörotoksiteye yol açtığı bilinmektedir. Bu çalışmada gadoliniumlu MRG tetkikleri ve karotid arter stentleme (KAS) işlemlerinin kontrast maddenin SAM'a geçisine etkisi değerlendirilmektedir.

___

  • 1) Ong E.M, Yeh I.B. High signal in the cerebrospinal fluid following prior gadolinium administration in a patient with renal impairment. Singapore Med J 2007; 48(11):e296–8.
  • 2) Bozzao A, Floris R, Fasoli F, et al. Cerebrospinal fluid changes after intravenous injection of gadolinium chelate: assessment by FLAIR MR imaging. Eur Radiol 2003; 13(3):592–7.
  • 3) Morris J.M, Miller G.M. Increased signal in the subarachnoid space on fluid-attenuated inversion recovery imaging associated with the clearance dynamics of gadolinium chelate: a potential diagnostic pitfall. Am J Neuroradiol 2007; 28(10):1964–7.
  • 4) Dechambre SD, Duprez T, Grandin CB, et al. High signal in cerebrospinal fluid mimicking subarachnoid hemorrhage on FLAIR following acute stroke and intravenous contrast medium. Neuroradiology 2000; 42(8):608–11.
  • 5) Gürer B, Yılmaz RE, Kahveci R, et al. Non-ionic contrast media neurotoxicity mimicking intracerebral hematoma. Acta Neurochir 2011; 153:419–420.
  • 6) Sawaya RA, Hammoud R, Arnaout S, et al. Contrast-induced encephalopathy following coronary angioplasty with iohexol. South Med J 2007; 100(10):1054–5.
  • 7) Leong S, Fanning NF. Persistent neurological deficit from iodinated contrast encephalopathy following intracranial aneurysm coiling. A case report and review of the literature. Interv Neuroradiol 2012; 18(1):33–41.
  • 8) Mamourian AC, Hoopes PJ, Lewis LD. Visualization of intravenously administered contrast material in the CSF on fluid-attenuated inversion-recovery MR images: an in vitro and animal-model investigation. Am J Neuroradiol 2000; 21:105–111
  • 9) Kanamalla US, Boyko OB. Gadolinium diffusion into orbital vitreous and aqueous humor, perivascular space, and ventricles in patients with chronic renal disease. AJR Am J Roentgenol 2002; 179:1350–52.
  • 10) Ogami R, Nakahara T, Hamasaki O, Araki H, Kurisu K. Cerebrospinal fluid enhancement on fluid attenuated inversion recovery images after carotid artery stenting with neuroprotective balloon occlusions: hemodynamic instability and blood-brain barrier disruption. Cardiovasc Intervent Radiol 2011; 34(5):936–41.
  • 11) Ray DE, Cavanagh JB, Nolan CC, et al. Neurotoxic effects of gadopentetate dimeglumine: behavioral disturbance and morphology after intracerebroventricular injection in rats. AJNR Am J Neuroradiol 1996; 17(2):365–73.
  • 12) Park KW, Im SB, Kim BT, et al. Neurotoxic manifestations of an overdose intrathecal injection of gadopentetate dimeglumine. J Korean Med Sci 2010; 25(3):505–8.
  • 13) Arlt S, Cepek L, Rustenbeck HH, et al. Gadolinium encephalopathy due to accidental intrathecal administration of gadopentetate dimeglumine. J Neurol 2007; 254(6):810–2.