Çocuklarda Akut Apandisit Tanısında Yeni Bir Belirteç Olarak Sistemik İmmün-İnflamasyon İndeksin Değerlendirilmesi

Amaç: Bu çalışmanın amacı, çocuklarda akut apandisit (AA) tanısında sistemik immün inflamasyon indeksinin (SII) yararlılığını belirlemektir. Gereç ve Yöntem: Bu çalışma retrospektif olarak yapıldı; AA ve kontrol grubu olmak üzere iki grup oluşturuldu. AA grubu nonperfore apandisit ve perfore apandisit olarak iki alt gruba ayrıldı. Gruplar yaş, cinsiyet, WBC, nötrofil, lenfosit ve trombosit sayısı, nötrofil-lenfosit oranı (NLR), trombosit-lenfosit oranı (PLR), sistemik immün inflamasyon indeksi (SII), C-reaktif protein (CRP) değerleri açısından karşılaştırıldı. Bulgular: Çalışmaya toplam 162 çocuk dahil edildi. AA grubunda 81, kontrol grubunda 81 çocuk vardı. AA grubuna dahil edilen 81 hastanın 31'i kız (%38,3), 50'si erkek (%61,7) olup, hastaların ortanca yaşı 11 (5) yıl idi. AA grubu ve kontrol grubu laboratuvar değerleri açısından karşılaştırıldığında. AA grubunda WBC sayısı, nötrofil sayısı, trombosit sayısı, NLR, PLR ve SII'nin anlamlı derecede yüksek olduğu ve lenfosit sayısının anlamlı derecede düşük olduğu bulundu (tümü için p

Anahtar Kelimeler:

Akut apandisit, çocuklar, sistemik immün-inflamasyon indeksi (SII)

Evaluation of Systemic Immune-Inflammation Index as Novel Marker in the Diagnosis of Acute Appendicitis in Children

Aim: The aim of this study was to determine the usefulness of systemic immune-inflammation index (SII) in the diagnosis of acute appendicitis (AA) in children Material and Method: This study was done retrospectively, and two groups were formed as AA and control group. AA group was divided into two subgroups as nonperforated appendicitis and perforated appendicitis. The groups were compared for age, sex, WBC, neutrophil, lymphocyte and platelet count, neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), systemic immune-inflammation index (SII), C-reactive protein (CRP). Results: The study included a total of 162 children. There were 81 children in the AA group and 81 in the control group. Of 81 patients included in the AA group, 31 were girls (38.3%) and 50 were boys (61.7%), and the median age of the patients was 11 (5) years. When the AA group and the control group were compared in terms of laboratory values. It was found that WBC count, neutrophil count, platelet count, NLR, PLR and SII in the AA group were significantly higher and lymphocyte count was significantly lower (p

Keywords:

Acute appendicitis, children, systemic immune-inflammation index (SII),

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