Esin KASAP, Mine GENÇ, Berrin KORKUT, Neslin SAHİN, Sibel DEMİR

CA 125 yüksekliği ile seyreden Meigs’ Sendromu: Olgu Sunumu

Postmenapozal hastalarda serumda artmış CA 125 birlikteliği ile beraber pelvik kitle,plevral efüzyon, masif asit varlığı genellikle kötü prognozu işaret eder.Bununla beraber doğru tanı ve tedavi için operasyon ve histopatolojik inceleme gereklidir çünkü yüksek CA125 düzeyi ovarian malignensi için yanlış pozitif olabilir.Biz bu yazıda postmenapozal hastada CA 125 yüksekliği ile seyreden sol ovarial fibromanın eşlik ettiği Meigs’ Sendromu olgusunu sunuyoruz.

Anahtar Kelimeler:

Meigs’ Sendromu, Asit, Plevral efüzyon, Serum CA 125

Meigs’ Syndrome with Elevated Serum CA125: Case Report

An elevated serum CA125 level in association with a pelvic mass,pleural effusion,and massive ascites usually signifies a dismal prognosis in a postmenopausal woman.However, surgery and histopathological examination are required for the correct diagnosis and treatment,since an elevated CA125 level can be falsely positive for ovarian malignancy.We present a case of Meigs’ syndrome due to left ovarian fibroma with elevated CA125 level in a postmenopausal woman.

Keywords:

Meigs’ syndrome, Ascites, Pleural effusion, Serum CA125,

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Chechia A, Attia L, Temime RB, Makhlouf T, Koubaa A: Incidence, clinical analysis, and management of ova- rian fibromas and fibrothecomas.Am J Obstet Gyne- col.2008, 199:471-474.
Sivanesaratnam V.,Dutta R., Jayalakshmi P.Ovarian fibroma Clinical and Histopathological Characteristics. Int.J.Gynecol.Obstet.1990;33:243-247
Paladini D.,Testa A.,Van Holsbeke C, Mancarı R, Tim- merman D,Valentin L. Imaging in gynecologicaldisease (5): clinical and ultrasound characteristics in fibroma and fibrothecoma of the ovary. Ultrasound Obstet Gynecol. 2009;34:188-195
Meigs JV, Cass JW: Fibroma of the ovary with ascites and hydrothorax with report of seven cases. Am J Obs- tet Gynecol 1937, 33:249–266.
Lurie S. Meigs’ syndrome: the history of the eponym. Eur J Obstet Gynecol Reprod Biol 2000;92:199–204.
Abad A, Cazorla E, Ruiz F, Aznar I, Asins E, Llixiona J. Meigs’ syndrome with elevated CA125: case report and review of the literature.Eur J Obstet Gynecol Rep- rod Biol 1999;82:97–9.
Timmerman D, Moerman P, Vergote I: Meigs’ syndro- me with elevated serum CA 125 levels: two case reports and review of the literature. Gynecol On- col.1995;59:405–408.