Association Between ABO Blood Group With Parkinson’s Disease

AbstractBackground/Aims:Parkinson's disease  is a common  neurodegenerative disease that seen in adulthood. Most prevelant symptoms are  resting tremor, rigidity, bradykinesia ,gait disturbance, and postural abnormalities.Disorders related with  ABO  blood group are infectious disease(cholera,helicobacter pylori,echerichia coli),cardiovascular disease,malignancies and allergic status.We objectived to elucidate the association between ABO  blood group and Parkinson's disease Materials -Methods: We investigated  retrospectively the files of 264 adult patients  who were diagnosed with Parkinson's disease and had blood type between January 2008 and December 2018 in neurology outpatient clinics included in the study Results: Distribution of  blood groups in patients as follows : ARh(+): 94(%35,6), ARh(-):15(%5,7),BRh(+):44(%16,7),BRh(-):8(%3), ABRh(+):18(%6,8),  ABRh(-):4(%1,5),0Rh(+):71(%26,9),0Rh(-):10(%3,8) Conclusions: When we consider the pathogenesis of Parkinson’s Disease , we think  of  the antigenic structure of blood groups may be effective in this process.

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