Bilateral kulak memesi yerleşimli Jessner lenfositik infiltrasyonu: Olgu sunumu ve Literatür taraması

Jessner lenfositik infiltrasyonu klinik olarak asemptomatik papül ve plaklarla, histopatolojik olarak da lenfositik infiltrasyonla karakterize bir hastalıktır. Hastalığın tanısı biyopsi ile histopatolojik olarak deride lenfositik infiltrasyonun gösterilmesi ile konmaktadır. Kırk dokuz yaşında erkek hasta dermatoloji polikliniğine her iki kulak memesinde kızarıklık ve kabarıklık şikâyeti ile başvurdu. Hastanın dermatolojik muayenesinde bilateral kulak memesi ve sol postauriküler bölgede eritemli, ödemli, yumuşak kıvamlı, papüller mevcuttu. Lezyonun deri biyopsisinde histopatolojik olarak CD3 (+) T lenfositler görüldü ve hastaya Jessner lenfositik infiltrasyonu tanısı kondu. Jessner lenfositik infiltrasyonun bilateral kulak memesi yerleşiminin nadir görülmesi nedeniyle olguyu sunmayı uygun bulduk.

Bilateral Jessner lymphocytic infiltration in the ear lobes: A case report and Literature review

Jessner lymphocytic infiltration is a disease characterized by a histopathological lymphocytic infiltration presenting with papules and plaques. The disease is diagnosed with biopsy via histopathologically showing the cutaneous lymphocytic infiltration. A 49-year-old male patient presented to dermatology outpatient clinic with redness and swelling in both ear lobes. The dermatologic examination showed erythematous, edematous and soft papules in the left post auricular region and in both ear lobes. The skin biopsy applied on the lesion revealed CD3 (+) T lymphocytes and the patient was diagnosed with Jessner lymphocytic infiltration. We present this case due to fact that bilateral Jessner infiltration in the ear lobes is a rare pathology.

___

  • Bagot M, Revuz J. Jessner-Kanof lesion and Borellia infection. J Am Acad Dermatol 1990;23:772-773.
  • Lipsker D, Mitschler A, Grosshans E, Cribier B. Could Jessner's lymphocytic infiltrate of the skin be a dermal variant of lupus erythematosus? An analysis of 210 cases. Dermatology 2006;213:15-22.
  • Toonstra J, Wildschut A, Boer J, et al. Jessner's lym- phocytic infiltration of the skin. A clinical study of 100 patients. Arch Dermatol 1989;125:1525-1530.
  • Dippel E, Poenitz N, Klemke CD, et al. Familial lym- phocytic infiltration of the skin: histochemical and molecular analysis in three brothers. Dermatology 2002;204:12-16.
  • Falco OB, Plewig G, Wolff HH, Burgdorf WHC. Derma- tology, 3rd edn. Berlin: Springer-Verlag, 2000: 1603- 1609.
  • Ashworth J, Morley WN. Jessner and Kanof's lympho- cytic infiltration of the skin: a familial variant. Dermato- logica 1988;177:120-122.
  • Remy-Leroux V, Leonard F, Lambert D, et al. Compari- son of histopathologic-clinical characteristics of Jess- ner's lymphocytic infiltration of the skin and lupus ery- thematosus tumidus: multicenter study of 46 cases. J Am Acad Dermatol 2008;58:217-223.
  • Jessner M, Kanof B. Lymphocytic infiltration of the skin. Arch Dermatol 1953;68:447-449.
  • Ghiringhelli F, Menarg C, Puig PE, et al. Metronom- ic cyclophosphamide regimen selectively depletes CD4+CD25+ regulatory T cells, restores T, NK effec- tor functions in end stage cancer patients. Cancer Im- munol Immunother 2007;56:641-648.
  • Ziemer M, Eisendle K, Müller H, Zelger B. Lympho- cytic infiltration of the skin (Jessner-Kanof) but not reticular erythematous mucinosis occasionally rep- resents clinical manifestations of Borrelia-associated pseudolymphoma. Br J Dermatol 2009;161:583-590.
  • Kaatz M, Zelger B, Norgauer J, Ziemer M. Lympho- cytic infiltration (Jessner-Kanof): lupus erythematosus tumidus or a manifestation of borreliosis? Br J Derma- tol 2007;157:1304.
  • Singh K, Dawar R, Ramesh V. Lymphocytic infiltration of skin of Jessner-Kanof masquerading as borderline leprosy. Indian J Lepr 1985;57:804-806.
  • Sparsa L, Afif N, Goetz J, et al. Jessner-Kanof disease induced by leflunomide: a dermal variant of cutaneous lupus? Rheumatol Int 2011;31:255-258.
  • Schepis C, Lentini M, Siragusa M, Batolo D. ACE inhibitor-induced eruption resembling lymphocytic in- filtration (of Jessner-Kanof) and lupus erythematosus tumidus. Dermatology 2004;208:354-355.
  • Nolden S, Casper C, Kuhn A, Petereit HF. Jessner- Kanof lymphocytic infiltration of the skin associated with glatiramer acetate. Mult Scler 2005;11:245-248.
  • Caroli UM, Berner D, Schlegel C, et al. Lymphocytic infiltration of the skin Jessner-Kanof after treatment with a hydroquinone containing bleaching cream. Arch Dermatol 2006;142:1655-1656.
  • Weinberg JM, Rokk AH, Lessin SR. Molecular diagno- sis of lymphocytic infiltrates of the skin. Arch Dermatol 1993;129:1491-1500.
  • Odom RB, James WD, Berger TG. Andrew's Disease of the skin, 9th edn. Philadelphia: WB Saunders Com- pany, 2000:918-942.
  • Ardavanis A, Orphanos G, Skafida S, et al. Coinciden- tial successful treatment of Jessner-Kanof disease with chemotherapy. Ann Oncol 2008;19:1360-1361.
  • Michel JL, Perrin D. Pulsed dye laser treatment for Jessner's lymphocytic infiltration of the skin. Ann Der- matol Venereol 2010;137:803-807.
Journal of Clinical and Experimental Investigations-Cover
  • Başlangıç: 2010
  • Yayıncı: Sağlık Araştırmaları Derneği
Sayıdaki Diğer Makaleler

Laparoskopik feokromasitoma cerrahisinde anestezi yönetimi: Olgu sunumu

Abdullah OĞUZ, Abdulmenap GÜZEL, Hakan AKELMA, Erdal DOĞAN, Zeynep YILDIRIM BAYSAL, Gönül KAVAK ÖLMEZ, Haktan KARAMAN

Airway management in a pediatric patient with post-burn neck contracture using i-gel

Fikret SALIK, Mustafa DURĞUN, Hayrettin DAŞKAYA, Taner ÇİFTCİ, Caferi Tayyar SELÇUK, Mehmet Beşir YILDIRIM

Obstrüktif uyku apne sendromlu hastalarda uyku parametreleri ile oksidatif stres arasındaki ilişki

Süreyya YILMAZ, Yılmaz PALANCİ, Hatice YÜKSEL, Hadice ŞEN SELİMOĞLU, Abdurrahman ABAKAY, Özlem ABAKAY, Abdullah Çetin TANRIKULU

Comparison of the hemodynamic effects of etomidate between hypertensive and normotensive patients

Ferda YILMAZ İNAL, Hayrettin DAŞKAYA, Yavuz GÜN, Taner ÇİFTÇİ, Sinan UZMAN, Mehmet TOPTAŞ, Mustafa DEMİR

İdrar kültürü testi gerekliliğini öngörmede tam otomatik idrar analizi sonuçlarının performansı

İbrahim KAPLAN, Gülten TOPRAK, Osman EVLİYAOĞLU, Hatice YÜKSEL, Seyit KUŞ, Tuba DAL

Fibrin sealant as a carrier for sustained delivery of antibiotics

Ismail ERSAN, Selçuk KARA, Hasan Ali TUFAN, Baran GENCER, Sedat ARİKAN, Ahmet VURAL, Ahmet UNVER

Plörezinin nadir bir nedeni: Erişkin Still Hastalığı

Umut Sabri KASAPOĞLU, İlim IRMAK, Dilek YAVUZ, Mehmet Fatih AKDOĞAN, İpek ERDEM, Canan ÖNEŞ, Fatma TOKGÖZ, Naim ULUSAN, Şule ÇAKAR, Armağan HAZAR

A multi-centric prospective study: Anxiety and associated factors among parents of children undergoing mild surgery in ENT

Mehmet AKDAĞ, Abdullah ATLI, İsmail TOPÇU, Baver SAMANCI, Zeynep YILDIRIM BAYSAL

Oxidative and antioxidative responses in submandibular and parotid glands of rats exposed to long-term extremely low frequency magnetic field

Süleyman DAŞDAĞ, Mehmet AKDAĞ, Mehmet Zülküf AKDAĞ, Özcan EREL

Primer beyin tümörleri: Proton manyetik rezonans spektroskopik analiz ve histopatolojik korelasyon

Bülent MIZRAK, Çağatay ÖNAL, Özlem AYDAGÜN, Kaya SARAÇ, Alpay ALKAN, Abdurrahim DUSAK