Isolated Triterpenes from Stingless Bee Lisotrigona furva Propolis in Vietnam

Yayın Aralığı: Yılda 2 Sayı
Başlangıç: 2018
Yayıncı: Oktay YILDIZ

Stingless bees of the genus Lisotrigona are uncommon species found in India and South East Asian countries. Several Lisotrigona species including L. cacciae, L.carpenteri and L. furva from Vietnam have been described. There has been no information on the chemical constituents and bioactivity of Lisotrigona stingless bee propolis in Vienam. Our goal of this work is to investigate the chemical constituents of the stingless bee Lisotrigona furva propolis collected in Binhdinh province, Vietnam. Using combined chromatographic methods, several triterpenes including mangiferolic acid (1), occotilones I (2) and II (3), dipterocarpol (4), hydroxyhopanone (5) and (13E,17E)-polypoda-7,13,17,21-tetraen-3β-ol (6) were isolated from the ethyl acetate extract of Lisotrigona furva propolis. The chemical structures of isolated compounds were identified by MS, NMR spectral analysis. Compound 5 and 6 were isolated for the first time from stingless bee propolis.

Keywords:

Lisotrigona furva propolis, NMR,

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1. Nguyen, H. X., Nguyen, M. T., Nguyen, N. T., & Awale, S. (2017). Chemical Constituents of Propolis from Vietnamese Trigona minor and Their Antiausterity Activity against the PANC-1 Human Pancreatic Cancer Cell Line. Journal of natural products, 80(8), 2345-2352.
2. Sanpa S., Popova M., Bankova V., Tunkasiri T., Eitssayeam S., Chantawannakul P. (2015). Antibacterial compounds from propolis of Tetragonula laeviceps and Tetrigona melanoleuca (Hymenoptera: Apidae) from Thailand. PLoS One, 10(5), e0126886.
3. Yoon, N. Y., Min, B. S., Lee, H. K., Park, J. C., & Choi, J. S. (2005). A Potent Anti-complementary acylated sterol glucoside fromOrostachys japonicus. Archives of pharmacal research, 28(8), 892.