Biyopestisit Emamektin Benzoat’ın Oreochromis niloticus'un Dokularında Toksik Etkilerinin Asetilkolinesteraz Enzim Aktivitesiyle Belirlenmesi

Bu çalışmada emamectin benzoate’ın Oreochromis niloticus’da AChE aktivitesi üzerine etkileri araştırılmıştır. Balıklar 110 ve 220 µg/L emamectin benzoate etkisine 96 saat ve 14 günlük sürelerle bırakılarak beyin, karaciğer ve böbrek dokularında asetilkoinesteraz (AChE) aktiviteleri belirlenmiştir. Emamectin benzoate maruz bırakılan O. niloticus'un beyin, karaciğer ve böbrek dokularında asetilkoinesteraz (AChE) enzim aktivitesi kontrol değerleriyle ile karşılaştırıldığında önemli değişiklikler belirlenmiştir Emamectin benzoate’a maruz bırakılan O. niloticus'un beyin, karaciğer ve böbrek dokularında AChE aktivitesi kontrol değerleriyle ile karşılaştırıldığında tüm sürelerde azaldığı belirlenmiştir.

Anahtar Kelimeler:

Emamectin Benzoate, Oreochromis niloticus, Asetilkoinesteraz, AChE, toksisite

Determination of Toxic Effects of Biopesticide Emamectin Benzoate in the Tissues of Oreochromis niloticus by Acetylcholinesterase Enzyme Activity

In this study, the effects of emamectin benzoate on the AChE activity in Oreochromis niloticus were investigated. Fishes were exposed to 110 and 220 μg / L of emamectin benzoate for 96 hours and 14 days to determine acetylcholinesterase (AChE) activities in brain, liver and kidney tissues. The were significant changes in asetilkoinesteraz (AChE) activities in brain, liver and kidney tissues of O. niloticus exposed to emamectin benzoate compared to controls. AChE activity in brain, liver and kidney tissues of O. niloticus, was reduced in all periods when compared to control values.

Keywords:

Emamectin Benzoate, Oreochromis niloticus, Acetylcholinesterase, AChE, toxicity,

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