Özlem ALTINKAYA, Cihan TOĞRUL, Eralp BAŞER, Levent ŞIRVAN, Ebru H. BİBEROĞLU, Müjdegül KARACA, Tayfun GÜNGÖR

Vajinanın primer malign melanomu: Olgu sunumu

Malign melanom yüksek malign potansiyeli olan deri ve mukozal membranları tutan bir nadir tümördür. Genel prognozu deri melanomlarından ve kutanöz melanomlardan daha kötüdür. 67 yaşında vajinal kanama ve vajende ele gelen kitle şikayetleriyle hastanemiz jinekolojik onkolojik cerrahi ünitesine başvuran hastanın, yapılan vajinal biyopsisinde primer vajinal malign melanom tespit edildi. Takiben geniş lokal eksizyon yapıldı.Postoperatif dönemde interlökin 2α ile adjuvan kemoterapi tedavisi yapıldı. Malign melanom, kadın genital sisteminde nadir görülen bir tümör olmasına rağmen,ileri yaş hastalar rutin jinekolojik muayene esnasında dikkatli inspeksiyonla değerlendirilmeli, şüpheli pigmente lezyonlardan biyopsi yapılmalıdır. Bu tümörlerin prognozu oldukça kötüdür, uygulanan tedaviye rağmen yüksek düzeyde rekürrens saptanır ve uzun dönem sağkalım oranları düşüktür. Primer tedavi yöntemi cerrahidir.

Primary malign melanoma of vagina: Case report

Malignant melanoma, a rare tumor of the skin and mucosal membranes has high invasion potential. Overall prognosis of mucosal melanoma is worse than cutaneus melanomas. A 67 year old woman with primary malignant vaginal melonoma who was treated surgically with wide local excision and postoperatif adjuvant chemotherapy with interferon 2α was presented. Although malignant melanoma of the female genital tract is uncommon,elderly patients should undergo regular gynecologic examinations. Suspicious pigmented lesions should biopsied; however, the prognosis is poor and these tumors are associated with high rate of recurrence and low long term survival. Surgery is the cornerstone of the treatment.

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