Berna SAYGIN HEKİMOĞLU, Atalay DEMİREL, Didem ARMAN

Neonatal hiperbilirubineminin prediktörü olarak umblikal kord kanı kırmızı hücre dağılım genişliği

Amaç: Yenidoğanların doğum sonrası erken taburcu edilmesi, çoğunlukla neonatal hiperbilirubinemi nedeniyle hastaneye yeniden yatış riskine yol açar. Bu nedenle hiperbilirubinemi riski yüksek olan yenidoğanların erken teşhisi önemlidir. Kırmızı hücre dağılım genişliği (RDW), rutin tam kan sayımında bulunan basit bir testtir. Bu çalışmada, hiperbilirubinemi gelişme riski yüksek olan yenidoğanları belirlemek için kord kanı kırmızı hücre dağılım genişliği (RDW) düzeylerinin kullanılıp kullanılamayacağını değerlendirmeyi amaçladık. Gereç ve yöntem: Ocak-Haziran 2017 tarihleri arasında hastanemizde doğan ve kordon kanı örneği alınan tüm term bebeklerin verileri geriye dönük olarak incelendi. Kord kanı RDW, kord kanı bilirubin, yenidoğan/anne kan grupları ve direkt Coombs testi (DCT) sonuçları analiz edildi. Bulgular: Çalışmaya toplam 175 yenidoğan dahil edildi. 58 yenidoğana postnatal ilk 48 saatte fototerapi verildi. Hiperbilirubinemili yenidoğanlarda ortalama kord kanı RDW düzeyleri kontrollere göre anlamlı derecede yüksekti (18±1.6'ya karşı 16.4±1.0, p

Anahtar Kelimeler:

RDW, umblikal kord kanı bilirubin, yenidoğan, hiperbilirubinemi, hemolitik hastalık

Umbilical cord blood red cell distribution width as a predictor of neonatal hyperbilirubinemia

Aim: Early postnatal discharge of newborns leads to the risk of hospital readmission, mostly due to neonatal hyperbilirubinemia. Therefore, early identification of newborns at high risk of hyperbilirubinemia is important. In this study, we aimed to evaluate whether cord blood red cell distribution width (RDW) levels could be used to identify newborns at high risk of developing hyperbilirubinemia. Material and methods: The data of all term infants who were born in our hospital between January and June 2017 whose cord blood samples were examined were reviewed retrospectively. Cord blood RDW, cord blood bilirubin, newborn/mother’s blood groups and direct Coombs’test (DCT) results were analyzed. Results: A total 175 newborns were included. Phototherapy was required 58 newborns in the first 48 hours postnatally. The mean cord blood RDW levels among newborns with hyperbilirubinemia was significantly higher compared to controls (18±1.6 vs. 16.4±1.0, p

Keywords:

RDW, umbilical cord blood bilirubin, newborn, hyperbilirubinemia;, hemolytic disease,

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