Gülbanu HORZUM, Tülin SEVİM, Güliz ATAÇ, Gökay GÜNGÖR, Adnan SOMAY

CHURG-STRAUSS SENDROMU (OLGU SUNUMU)

On üç yıldır astım nedeniyle izlenen 31 yaşındaki kadın hasta nefes darlığı, göğüs ağrısı ve cilt lezyonları ile başvurdu. Periferik kanda %52 oranında eozinofili saptandı. Akciğer grafisinde kardiyomegali ve sağ diyafragma üzerinde nonhomojen retiküler gölge artışı mevcuttu.Yapılan cilt biyopsisinde papiller dermiste kapiller damarlar çevresinde ve retiküler dermiste küçük damarlardan birinde mononükleer iltihabi hücre infiltrasyonu görülerek CSS ile uyumlu bulundu. Klinik, laboratuvar ve histopatolojik bulgularla CSS olarak kabul edilen hastaya kortikosteroid tedavisi başlandı. Tedavinin 15.gününden itibaren klinik ve laboratuvar yanıt alınan hasta sunulmuştur.

Anahtar Kelimeler:

Churg-Strauss sendromu, vaskülit, astım

CHURG-STRAUSS SYNDROME (CASE REPORT)

A 31 year-old woman with 13-year history of asthma was admitted to our center because of dyspnea, chest pain and skin lesions. Peripheral blood count showed eosinophilia, 52%. Chest x-ray showed cardiomegaly and nonhomogeneous reticuler infiltration on the right hemidiaphragma. There were mononucleer inflammatory infiltrate in the papiller and reticuler dermis in the biopsy material which was obtained from skin lesions.This histopathological features were consistent with CSS. As the clinical, laboratory and histopathological features led to a diagnosis of CSS, steroid treatment was started. Our patient showed radiological and clinical remission after the fifteenth days of therapy.

Keywords:

Churg-Strauss syndrome, vasculitis, asthma,

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