AKCİĞER METASTAZLI OPERE TİROİD KARSİNOMU

Tiroid karsinomları endokrin sistemin en sık görülen malignitesidir. Tiroid papiller karsinom %75-85 ile en sık görülen tipdir, aynı zamanda prognozu en iyi olan tiroid karsinomudur. Kadınlarda daha fazla görülmesine karşın erkeklerde mortalitesi daha yüksektir ve en sık uzak metastazı akciğerlere yapar. Nefes darlığı, öksürük, kilo kaybı, kanlı balgam çıkarma şikayetleri ve akciğer grafisinde milier-mikronodüler lezyonları ile dış merkezde milier akciğer tüberkülozu tanısı alan ve tüberküloz tedavisi başlanan olgu şikayetlerinin devam etmesi üzerine poliklinik başvurusu ile yatırıldı. Yapılan tetkikler sonucu tiroid karsi-nomunun akciğer metastazı saptandı. Olgu milier akciğer tüberkülozu ile karıştırılması, nüks olmadan akciğere yaygın metastaz yapması ve tipik radyolojisi nedeni ile sunulmuştur.

LUNG METASTASIS OF OPERATED THYROID CARCINOMA

Thyroid carcinomas are the most common malignancies of the endocrine systems. Thyroid papillary carcinoma is the most frequent type of thyroid carcinomas with 75-85% and its prognosis is better than the other types. It presents more frequently at women but it is more mortal at men and the most usual metastasis appears on lungs. A-61 year old man who had diagnosed as miliary tuberculosis with shortness of breath, cough, hemoptisy, weight loss and with the radiology of miliary-micronodular lesions and had been treated with antituberculosis drugs at a different hospital was referred to our clinic, since his complaints have still occured. After the examinations, the lung matastasis of thyroid carcinoma was determinated. We present this case because of thyroid carcinoma has typical radiological images, it can be confused with milier tbc, it can occur with diffuse lung metastases without relaps.

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  • 1. Hirabayaski RN, Lindsay RL. Carcinoma of the thyroid gland: A Statistical study of 390 patients. J Clin Endocrino Metab 1961; 21: 1596-1610.
  • 2. Goldsmith SJ. Thyroid Carcinoma In: Khalkholi I, Maciblant JC, Goldsmith SJ, Editors Nuclear Oncology: Diagnosis and Therpy. 1th ed. Philladelphia: Lippincott-Raven Publischers, 2001: 197.
  • 3. Hundahl S, Flemning I, Fremgen A. Merck H. A national cancer data baser report on 53.856 cases of thyroid carcinoma treated in the us, 1985-1995. Cancer 1998; 83: 2638-48.
  • 4. Schlumberger MJ, Filetti S, Hay ID. Nontoxic goiter and thyroid neoplasia. Larsen PR, Kronenberg HM, Melmeds, Plonsky KS (Ed). Williams Textbook of Endocrinology. Tenth edition. Philadelphia, WB Sauderns Campany, 2003: 457-90.
  • 5. Carling T, Udelsman R. Thyroid tumors In: De Vita VT, Hellman S, Rosenberg SA, eds: Cancer. Prrinciples and Practice of Oncology. 7th Edition, Philadelphia. Lippinocott Williams & Wilkins, 2005. ch 34 pp 1502-19.
  • 6. Mazzaferri EC, Kloos RT. Current approaches to primary therapy for papillerygland follicular thyroid cancer. J Clin Endocrinol Metab 2001; 86(4): 1147-63.
  • 7. Muno-Cacho CA, Ku NN. Tumors of the thyroid gland: histologic and cytologic features part I.Cancer Control 2000; 7(3): 276-87.
  • 8. Wartofsky I. Papillary carcinoma: Clinical aspects In: Wartofsky I, eds: Thyroid Cancer: A Comprecheniue Guide to Clinical Management, Totowa New Jersey: Humana Pres, 2000.ch 16, pp 185-192.
  • 9. Mazafferi EL. Thyroid cancer. In Becker KL. eds: Principhs and Practice of Endocrinology and Metahdism. Philadelphia: Lippincott Williams & Wilkins 2001, ch40, pp 382-396.
  • 10. Lin JD, Chao TC, Chao SC, Hsuch C. Papillary thyroid carcinomas with lung metastases. Thyroid 2004; 14(12); 1091-6
  • 11. Ilgan S, Karacalio¤lu AO, Pabusus Y, Atac GK, Arslan N, Öztürk E, Günalp B, Özgüven MA. Iodine-131 treatment and high-resolution CT: results in patients with lung metastases fram differentiated thyroid carcinoma. Eur J Nucl Med Mol Imaging 2004; 31(6): 825-30.