RABDOMİYOLİZE BAĞLI AKUT BÖBREK YETMEZLİĞİ GELİŞEN HASTALARIN, KARAKTERİSTİK ÖZELLİKLERİ VE RİSK FAKTÖRLERİ: TEK MERKEZ DENEYİMİ

Giriş: Ülkemizde deprem sıklığının yüksek olması ve iş kazalarının sık görülmesi sebebiyle rabdomiyoliz sıkgörülmektedir. Rabdomiyolizin en önemli komplikasyonlarından birisi akut böbrek yetmezliği olması nedeni ileklinisyenlerin akut böbrek yetmezliğini önlemek ve ilişkili komplikasyonlarına dikkat çekmek amacıyla rabdomiyolizilişkili böbrek yetmezliğinin sıklığı, klinik özellikleri ve risk faktörlerini tanımlamak ve bu hastalara klinik yaklaşımdakolaylık sağlamak amacı ile bu retrospektif analizi planladık.Gereç ve Yöntem: 2016-2019 tarihleri arasında Türkiye Ankara Atatürk Eğitim Araştırma Hastanesi Acil servis,Nefroloji ve İç Hastalıkları Polikliniklerine başvurusunda rabdomiyoliz tanısı alan, İç hastalıkları ve Nefrolojikliniklerinde yatarak tedavi gören 81 erişkin hastanın kayıtları retrospektif olarak incelendi.Bulgular: 81 hasta (hastaların ortalama yaşı 59.7 ± 20.8’di, hastaların 54’ü (% 66.6) erkek, 27’si (%33.3) kadındı)çalışmaya dahil edildi. Etiyolojik açıdan 23 hasta ile en sık sebep enfeksiyondu. Akut böbrek yetmezliğibulunmayan hastaların bulunanlara göre serum üre, kreatinin, LDH, fosfor, geliş CK düzeyi, 24 saat sonraki CKdüzeyi, 48 saat sonraki CK düzeyi, en yüksek CK düzeyi anlamlı olarak daha düşük saptandı. (p

FREQUENCY, CHARACTERISTICS AND RISK FACTORS OF RHABDOMYOLYSIS RELATED ACUTE RENAL FAILURE: SINGLE CENTER EXPERIENCE

Introduction: Rhabdomyolysis is a common condition because of high rate earthquake risk of our country and occupational accidents. Acute renal failure is one of the most important complication of rhabdomyolysis. We conducted this retrospective study to determine the frequencyof this clinical entity, and to predict acute renal failure after rhabdomyolysis as a complication. In addition, we aimed to detect the frequency rhabdomyolysis related acute renal failure, clinical features and risk factors to provide convenience in the treatment algorithm of this disease. Material and Method: In this retrospective analysis, patients who admitted to our clinic between 2016 and 2019 with the diagnosis of rhabdomyolysis and treated inpatient service were enrolled in the study. The patients' data were extracted from hospital records retrospectively. Demographic information (identity numbers, age, gender), etiological İzmir Eğitim ve Araştırma Hastanesi Tıp Dergisi (Medical Journal of İzmir Hospital) 25 (2): 101-106, 2021 102 İzmir Eğitim ve Araştırma Hastanesi Tıp Dergisi (Medical Journal of İzmir Hospital) factors, laboratory examination results (urea,creatinine, LDH, phosphor, and initial creatinine phosphokinase (CK) level, CK level 24thhour, CK level 48th hour and highest CK level were recorded and analyzed. Results: Totally 81 patients enrolled in this study. Mean age of all patients was 59.7 ± 20.8 (Mean±SD). Of 81 patients, 54 (66.6%) were male and 27 (33.3%) were female. Infection was the most frequent cause in 23 patients as an etiological factor. Serum urea, creatinine, LDH and phosphor levels and initial CK level, CK (24th hour), CK (48th hour) and highest CK levels were determined to be significantly low in patients without acute renal failure in comparison with the patients with acute renal failure (p

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