Intercellular adhesion molecule-1 (ICAM-1) and C-Reactive Protein (CRP) levels in Calves Naturally infected with Mycoplasma bovis

Mycoplasma bovis is one of the most important pathogens causing pneumonia worldwide. In this study, it was aimed to determine intercellular adhesion molecule-1 (ICAM-1) and C-reactive protein (CRP) levels in calves infected with Mycoplasma bovis. The animal material of the study consisted of 30 calves including 20 simmental calves with pneumonia due to Mycoplasma bovis at 2-4 months of age and 10 healthy calves at the same age and the race. Serum levels of intercellular adhesion molecule-1 (ICAM-1) and C-reactive protein (CRP) were determined in calves infected M. bovis and control group. Serum levels of intercellular adhesion molecule-1 (ICAM-1) and C-reactive protein (CRP) were found to be statistically higher in the calves with pneumonia than in the control group (P<0.01). A positive correlation between serum ICAM-1 concentrations and Mycoplasma bovis titers (increases in coefficient ratios) were statistically significant (r=0.664), indicating a positive correlation between serum ICAM-1 and CRP levels and titers of Mycoplasma bovis in the calves with pneumonia. As a result, it was observed that serum intercellular adhesion molecule-1 (ICAM-1) and C-Reactive Protein (CRP) concentrations were increased in infected pneumonia with Mycoplasma bovis. It is considered useful to consider these parameters in evaluating the prognosis of pneumonia cases of Mycoplasma bovis origin and the efficacy of applied treatment.

Anahtar Kelimeler:

Calf, Mycoplasma bovis, C-Reactive Protein, Intercellular adhesion molecule-1

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