Williams CHİNTEM D.G., İsmaila Yada SUDİ, Manaseh SILAS

Toxicity and phytochemical analysis of petroleum-ether, ethanolic and aqueous extracts of Ceratotheca sesamoides

This research investigated the toxicity and phytochemical analysis of aqueous ethanol and pet ether extract of Ceratotheca sesamoides leaves in albino wistar rats. Qualitative and quantitative phytochemical screening of Ceratotheca sesamoides were carried out. The result of the toxicity test revealed that aqueous extracts of Ceratotheca sesamoides leaf did not show any fatality with dosage range (300 mg-5000 mg). This shows that the LD50 is greater than 5000 mg/Kg body weight.The phytochemical investigation shows the presence of glycoside, carbohydrate and alkaloid in all the extract and only flavonoid was found in Aqueous and ethanol extracts. This shows that C. sesamoides is safe for consumption and is rich in polyphenols, flavonoids and tannins.

Keywords:

toxicity phytochemical, fatality, Ceratotheca sesamoides,

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