Hadeil AHMED, Abdalbasit MARIOD, Tarig HAMMODA

The chronic toxicity studies of camellia seed oil containing tea saponins on mice blood and organs

Tea saponins are normal non-ionic surfactants with surface-dynamic (surfactant) properties, they are separated from the Camellia oleifera seed as a likely source. These saponins are more prominent than 10% of the camellia seed and are used as a natural tenside that is thoughtful to the environment. Camellia seed oil containing tea saponins was used as the main material; we set three groups: Low, Medium, and High groups with different doses. 30 days feeding in mice experiment. Mice blood and organs were taken to analyze the chronic toxicity; in 30 d used olive oil as a control group. The results showed, there were significant differences in some index and there were no vital changes in the other indicators. According to the analysis of the results, camellia oil containing tea saponins has some toxic effect in functions of viscera, peripheral blood in mice. The results offer a theoretical basis for the utilization and safety of camellia oil containing tea saponins and promote the vital significance of the in taking securely and healthily of camellia oil. The chronic toxicity of camellia oil containing tea saponin was not strong, feeding on mice in a high dose 30 days each viscera and other features and growth has no significant impacts.

Keywords:

Camellia seed oil, , tea saponins, , mice, , blood, , organs, hemogram, , histology,

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