Detection of Micro Calcifications in Mammogram Images Using Texture Analysis and Logistic Regression

Micro-calcification in the breast is a symptom of breast cancer. Therefore, detection of micro-calcification in mammogram image plays an important role in the early diagnosis of breast cancer. Because the mammogram images are 2-dimensional, different tissues in the breast are seen on top of each other. Therefore, it is a compelling task for radiologists to identify the masses found in mammogram images. There are different methods for detecting micro-calcification in mammogram images. In this study, different image processing techniques were applied on mammogram images and a region of 80x80 pixel was taken from breast tissue. Texture features of this region were extracted using co-occurrence matrix and classified by logistic regression analysis. Classification success of 88% was achieved with the proposed model.

___

[1] J. B. Li, “Mammographic image based breast tissue classification with kernel self-optimized fisher discriminant for breast cancer diagnosis” Journal of Medical Systems, vol. 36, no. 4, pp. 2235-2244, 2012.

[2] J. Ferlay, M. Colombet, I Soerjomataram, C. Mathers, D.M. Parkin, M. Pineros, A. Znaor, F. Bray, “Estimating the global cancer incidence and mortality in 2018: GLOBOCAN sources and methods” International Journal of Cancer, vol. 144, no. 8, pp. 1941-1953, 2019.

[3] J. G. Melekoodappattu and P.S. Subbian, “A Hybridized ELM for Automatic Micro Calcification Detection in Mammogram Images Based on Multi-Scale Features” Journal of Medical Systems, vol. 43, no. 7, pp. 183, 2019.

[4] V. Ramachandran and V. Kishorebabu, “A Tri- State Filter for the Removal of Salt and Pepper Noise in Mammogram Images” Journal of Medical Systems, vol. 43, no. 2, pp. 40, 2019.

[5] A. Taliafico, G. Mariscotti, M. Durando, C. Stevanin, G. Tagliafico, L. Martino, B. Bignotti, M. Calabrese, N. Houssami, “Characterisation of microcalcification clusters on 2D digital mammography (FFDM) and digital breast tomosynthesis (DBT): does DBT underestimate microcalcification clusters? Results of a multicentre study” Eur Radiol, vol. 25, no. 1, pp. 9-14, 2015.

[6] H. Cai, Q. Huang, W. Rong, Y. Song, J. Li, J. Wang, J. Chen, L. Li, “Breast Microcalcification Diagnosis Using Deep Convolutional Neural Network from Digital Mammograms” Journal of Computational and Mathematical Methods in Medicine, vol. 2019, no. 2717454, pp. 10, 2019.

[7] M. Sharkas, M. Al-Sharkawy, D.A. Ragab, “Detection of Microcalcifications in Mammograms Using Support Vector Machine” UKSim 5th European Symposium on Computer Modeling and Simulation,16-18 Nov. 2011, doi: 10.1109/EMS.2011.23.

[8] B. Kurt, V. Nabiyev, K. Turhan, “An Automated Computer-Aided Detection (CADe) And Diagnosis (CADx) System For Breast Microcalcifications In Mammograms” Selcuk Univ J Eng Sci Tech, vol. 6, no. 3, pp. 355-376.

[9] T. M. A. Basile et al., “Microcalcification detection in full-field digital mammograms: A fully automated computer-aided system” Physica Medica, vol. 64, no. 4, pp. 1-9, 2019.

[10] J. Suckling, “The Mammographic Image Analysis Society Digital Mammogram Database Exerpta Medica” Paper presented at the International Congress Series, 1994.

[11] D. Vernon, “Machine Vision” Prentice-Hall, 1991.

[12] K. Joung-Youn, K. Lee-Sup, H. Seung-Ho, “An advanced contrast enhancement using partially overlapped sub-block histogram equalization” IEEE Transactions on Circuits and Systems for Video Technology, vol. 11, no. 4, pp. 475-484, 2001.

[13] M. Cui, S. Prasad, M. Mahrooghy, J. V. Aanstoos, M. A. Lee, L. M. Bruce, “Decision Fusion of Textural Features Derived From Polarimetric Data for Levee Assessment” IEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing, vol. 5, no. 3, pp. 970-976, 2012.

[14] N. Severoğlu, “Mammogram images classification using Gray Level Co-occurence Matrices” 24th Signal Processing and Communication Application Conference, 16-19 May 2016, doi: 10.1109/SIU.2016.7496106.

[15] H. Midi, S. K. Sarkar, S. Rana, “Collinearity diagnostics of binary logistic regression model” Journal of Interdisciplinary Mathematics, vol. 13, no. 3, pp. 253-267, 2010.