The study was carried out on hypotheses testing of variables of basic science teachers’ on academic performance students’ in Upper Basic Schools Kwara State, Nigeria. This target population for the study was all Basic Science Teachers in Kwara State, Nigeria, four hundred and sixty-nine (469) Public Upper Basic Schools. The researcher designed teachers' questionnaire and was administered to one hundred and thirty five (135) Basic science teachers that were selected from forty-five Upper Basic Schools in Kwara State. Researcher-designed validated questionnaire was used to extract data from the respondents on the teachers 'influence on the performance of students in Upper Basic Schools. Three research questions were raised with two hypotheses which were tested. Percentage, t-test statistics and ANOVA were used to analyze the facts collected. The finding showed that influence of Basic science teachers on the performance of students in Upper Basic Schools in Kwara State, Nigeria was significantly. It was also significant based on year of teaching experience and academic qualification of Basic science teachers. According to the findings, it is suggested that; the educational authorities and the school system should encourage the use of available resources by providing for them, the necessary materials that will influence Basic Science performance and enhance students learning. State government and proprietors of private secondary schools should organize seminars and workshops for science teachers on regular basis especially for the public schools’ science teachers. Professionally qualified Basic Science teachers should be allowed to teach Basic Science