By the drive of global competition based on innovating of cutting edge technology, more and more people within business functions need to have IT skills and will be involved in IT processes, decisions and operations. Therefore business and IT need to be better integrated as they are becoming intertwined. Since poor integration of different IT systems incongruent with business needs is accepted as one of the major explanations for the failure of effective accomplishment of the business and IT goals and objectives of organizations, this paper tries to analyze the governance of IT governance infrastructures of Regional Development Agencies (RDAs) in Turkey that can be promoted with COBIT-5 model with which the governance of IT enterprise come to the fore at the end of 2012 by Information Systems Audit and Control Association (ISACA). This paper introduces holistic and integrated application of COBIT-5 framework in brief to improve and promote the level of e-governance from a theoretical point of view