DESENDAN SEYİRLİ BİR GUİLLAİN BARRE SENDROMU OLGUSU
Guillain Barre Sendromu (GBS), sıklıkla simetrik güçsüzlük ve arefleksi ile karakterize akut inflamatuar polinöropatidir. Geçirilmiş bakteriyel veya viral enfeksiyonların tetiklediği otoimmün bir hastalık olduğu kabul edilmektedir. Çocukluk çağı GBS'de mortalite %1-2 oranındadır ve genellikle solunum yetersizliğine bağlı olarak gelişir. Burada 14 yaşında viral enfeksiyon sonrası GBS gelişen bir erkek çocuk sunularak bu sendromun klinik özellikleri gözden geçirildi.Guillain, Barre ve Strohl 1916’da 1.Dünya Savaşı sırasında iki askerde spontan olarak iyileşen progresif motor bozukluk bildirdiler. Benzer olgular daha önce de bildirilmesine rağmen, Guillain ve ark. reflekslerin bir periferik sinir etkilenmesine bağlı olarak kaybolduğunu ve beyin omurilik sıvısında protein artışıyla birlikte hücre sayısının normal oluşuyla Poliomiyelitten farklı bir hastalık olduğunu gösterdiler (1).
Anahtar Kelimeler:
Çocuk, Guillian-Barre Sendromu, Klinik bulgular
A CASE OF GUILLAIN BARRE SYNDROME WITH DESCENDANT COURSE
Guillain Barre Syndrome (GBS) is an acute inflammatory polyneuropathy characterized by symmetrical weakness and areflexia. It is considered to be an autoimmune disease triggered by bacterial or viral infections. The mortality is 1-2% in childhood GBS and it usually develops due to respiratory failure. We present a 14 years old boy with GBS developed after viral infection.Guillain Barre Syndrome (GBS) is an acute inflammatory polyneuropathy characterized by symmetrical weakness and areflexia. It is considered to be an autoimmune disease triggered by bacterial or viral infections. The mortality is 1-2% in childhood GBS and it usually develops due to respiratory failure. We present a 14 years old boy with GBS developed after viral infection.
Keywords:
Child, Clinical findings, Guillain Barre Syndrome,
___
- Winer JB. Guillain-Barré syndrome: clinical variants and their pathogenesis. J Neuroimmunol. 2011; 231: 70-2.
- Asbury A, Cornblath DR. Assessment of current diagnostic criteria for Guillain-Barre Syndrome. Ann Neurol 1990; 27: 21-4.
- Ropper AH. The Guillain Barre syndrome. N Engl J Med 1992; 23: 1130-6.
- McGrogan A, Madle GC, Seaman HE, de Vries CS. The epidemiology of Guillain-Barré syndrome worldwide. A systematic literature review. Neuroepidemiology 2009; 32: 150- 63
- Rantala H, Uhari M, Niemela M. Occurrence, clinical manifestations, and prognosis of Guillain-Barre Syndrome, Arch Dis Child 1991; 66: 706.
- Menkes HJ: Immunologically mediated demyelinating diseases of the periferal nervous system, Guillain-Barre Syndrome. In: Menkes HJ,Sarnat BH eds. Textbook of Child Neurology. Philadelphia: Lippincott Williams and Wilkins 2000: 658-65.
- Kuwaba S, Mori M, Ogawara K et al. Indicators of rapid clinical recovery in Guillain Barre syndome. J Neurol Neurosurg Psychiatry 2001; 70: 560-2.
- Delanoe C, Sebire G, Landrieu P, Huault G, Metral S. Acute inflammatory demyelinating polyradiculopathy in children: Clinical and electrodiagnostic studies. Ann Neurol 1998; 44: 350-6.
- Visser LH, van der Meche FG, Meulstee J et al. Cytomegalovirus infection and Guillain- Barre syndrome: The clinical, electrophysiologic, and prognostic features. Dutch Guillain- Barre Study Group. Neurology 1996; 47: 668-73.
- Yuki N, Ang CW, Koga M, et al. Clinical features and response to treatment in Guillain- Barre Syndrome assosiated with antibodies to GM1b ganglioside Ann Neurol 2000; 47: 314-21.
- Italian Guillain-Barre Study Group. The prognosis and main prognostic indicators of Guillain Barre syndrome. A multicentre prospective study of 297 patients. Brain 1996; 119: 2053-61.
- Bradshaw DY, Jones HR Jr. Guillain-Barre syndrome in children: Clinical course, electrodiagnosis, and prognosis. Muscle Nerve 1992; 15: 500-6.
- Moulin DE, Hagen N, Feasby TE, et al. Pain in Guillain-Barre syndrome. Neurology 1997; 48: 328-31.
- Larsen A, Tobias JD. Guillain-Barre syndrome presenting with symptoms of upper airway obstruction. Pediatr Emerg Care 1994; 10: 347-8.
- Briscoe DM, Mc Menamin JB, O'Donohoe NV. Prognosis in Guillain-Barre syndrome Arch Dis Child 1987; 62: 733-5.
- Jones HR. Childhood Guillain-Barre syndrome: Clinical presentation, diagnosis, and therapy. J Child Neurol 1996; 11: 4-12.
- Yayın Aralığı: Yılda 3 Sayı
- Başlangıç: 2023
- Yayıncı: Hatay Mustafa Kemal Üniversitesi Tıp Fakültesi Dekanlığı
Sayıdaki Diğer Makaleler
MEME METASTAZLARI: AYIRICI TANININ ÖNEMİ VE UYGUN KLİNİK YAKLAŞIM
Seçkin Akküçük, Akın Aydoğan, İbrahim Yetim
DESENDAN SEYİRLİ BİR GUİLLAİN BARRE SENDROMU OLGUSU
Fatmagül Başarslan, Cahide Yılmaz, Murat Tutanç, Vefik Arıca, Nilgün Üstün, Işıl Davarcı
SUBMANDİBULAR TÜKRÜK BEZİ KANALINDA TAŞ BULUNAN 4 YAŞINDA ÇOCUK OLGU
SİMULTANE BİLATERAL FASİYAL PARALİZİ İLE SEYREDEN MELKERSSONROSENTHAL SENDROMU: NADİR BİR VAKA