The investigation of incidence and radiological findings of gastrointestinal stromal tumor as a rare cause of abdominal mass

The investigation of incidence and radiological findings of gastrointestinal stromal tumor as a rare cause of abdominal mass

Aim: The aim of the present study was to evaluate the investigation of incidence and radiological findings of gastrointestinal stromal tumors (GIST) as a rare cause of abdominal mass, with current literature review.Material and Methods: Between February 2011 and May 2016, a total of 4,443 patients who underwent abdominal multislice computed tomography and magnetic resonance imaging due to the clinical indications for abdominal pain, abdominal swelling-mass were analyzed in our hospital. The retrospective cross-sectional study included forty-five patients, who were subsequently diagnosed with GIST histopathologically. Results: GIST was identified in 45 (1%) patients. Of the total 45 patients, 21 (47%) were men and 24 (53%) were female. The mean age was 55 years, ranging from 35 to 73 years. As a result of radiological examinations, the tumor location was stomach in 22 cases (49%), small intestine in 12 cases (27%) and colon in 9 cases (20%). The retroperitoneal localization was also found in 2 cases (4%). The average size of the lesions ranged between 2 and 15 cm. Malignant degeneration and omental metastasis were seen in 11 (24%) and 7 cases (16%) respectively.Conclusion: GIST is a rare cause of abdominal mass with an incidence of 1% in our region. They are most commonly localized in the stomach, rarely in the omentum/mesentery and retroperitoneum. The Malignant transformation is not frequent. Diagnosis and evaluations of mass can be made successfully by radiological imaging modalities.

___

  • Ayşegül Akdoğan Gemici, Osman Köneş, Ali Kocataş, Ahmet Tan Cimilli. Gastrointestinal Stromal Tümörlerin Klinik, Radyolojik ve Patolojik Bulgularının Değerlendirilmesi. Fırat Tıp Dergisi 2013;18(4):219-23.
  • Yüksel Küçükzeybek, Betül Bolat Küçükzeybek, Abdullah Altıntaş, Cengiz Demir. Gastrointestinal Stromal Tümörlerin Medikal Tedavisinde Güncel Açılımlar. Van Tıp Dergisi 2010;17:23-31.
  • Van Den Abbeele AD, Badawi RD. Use of positronemission tomography in oncology and its potential role to assess response to imatinib mesylate therapy in gastrointestinal stromal tumors. Eur J Cancer 2002;38:S60-5.
  • Blay JY, Bonvalot S, Casali P, Choi H, Debiec-Richter M, Dei Tos AP, et al. Consensus meeting for the management of gastrointestinal stromal tumors. Ann Oncol 2005;16(4):566-78.
  • Hong X, Choi H, Loyer EM, Benjamin RS, Trent JC, Charnsangavej C. Gastrointestinal stromal tumor: role of CT in diagnosis and in response evaluation and surveillance after treatment with imatinib. Radiographics 2006;26(2):481-95.
  • Bucher P, Villiger P, Egger JF, Buhler LH, Morel P. Management of gastrointestinal stromal tumours: from diagnosis to treatment. Swiss Med Wkly 2004;134:145-53.
  • Selcukbiricik F, Tural D, Oztürk MA, Dervisoglu S, Sager S, Hız M, et al. Gastrointestinal stromal tumor of the rectum with scapular metastasis: a case report. J Med Case Rep 2012;6:145.
  • Fletcher CD, Berman JJ, Corless C, Gorstein F, Lasota J, Longley BJ, et al. Diagnosis of gastrointestinal stromal tumors: a consensus approach. Hum Pathol 2002;33(5):459-65.
  • Bolukbasi H, Nazli O, Tansug T, Bozdag AD, Isgiider AS, Yaman I, et al. Gastrointestinal stromal tumors (GISTs): analysis of 20 cases. Hepatogastroenterology 2006;53:385-8.
  • Mustafa Şit, Fatih Kaya, Edip Erdal Yilmaz, Gülali Aktaş. Mide Fundusunda Nadir Yerleşimli Gastrointestinal Stromal Tümörü: Olgu Sunumu. Kocaeli Tıp Dergisi 2012;1(2):31-4.
  • Goettsch WG, Bos SD, Breekveldt-Postma N, Casparie M, Herings RM, Hogendoorn PC. Incidence of gastrointestinal stromal tumours is underestimated: results of a nation-wide study. Eur J Cancer 2005;41(18):2868-72.
  • Nilsson B, Bümming P, Meis-Kindblom JM, Oden A, Dortok A, Gustavsson B, et al. Gastrointestinal stromal tumors: the incidence, prevalence, clinical course, and prognostication in the preimatinib mesylate era--a population-based study in western Sweden. Cancer 2005;103(4):821-9.
  • Ma GL, Murphy JD, Martinez ME, Sicklick JK. Epidemiology of gastrointestinal stromal tumors in the era of histology codes: results of a population-based study. Cancer Epidemiol Biomarkers Prev 2015;24:298-302.
  • Reddy P, Boci K, Charbonneau C. The epidemiologic, health-related quality of life, and economic burden of gastrointestinal stromal tumours. J Clin Pharm Ther 2007;32(6):557-65.
  • Tran T, Davila JA, El-Serag HB. The epidemiology of malignant gastrointestinal stromal tumors: an analysis of 1,458 cases from 1992 to 2000. Am J Gastroenterol 2005;100(1):162-8.
  • Takizawa I, Morishita H, Matsuki S, Komeyama T, Emura I, Hara N. Primary gastrointestinal stromal tumor in the retroperitoneum. Int J Urol 2006;13(9):1245-8.
  • Engin G, Asoglu O, Kapran Y, Mert G. A gastrointestinal stromal tumor with mesenteric and retroperitoneal invasion. World J Surg Oncol 2007;5:121.
İnönü Üniversitesi Turgut Özal Tıp Merkezi Dergisi-Cover
  • ISSN: 1300-1744
  • Yayın Aralığı: 4
  • Yayıncı: İnönü Üniversitesi Tıp Fakültesi
Sayıdaki Diğer Makaleler

Efficacy of monopolar radiofrequency in middle and lower face laxity

Hilal GÖKALP

Hydrothorax caused by catheter malposition misdiagnosed via using plain radiography

Yasemin ALTUNER TORUN, Alper OZCAN, Ayse Betul ERGUL

Pemphigus vulgaris presenting as bleeding gums: A case report

Shruthi HEGDE, Subhas BABU, Sajad Ahmad BUCH, Shruthi RAO, Vidya AJILA

An unexpected complication: acute dystonic reaction following use of ondansetron

Resul YİLMAZ, Merve YEDİYILDIZ BULUN, Rabia YAMAN, Ahmet TOPAL

Periodontal health status of children with type 1 diabetes mellitus

Ceren GOKMENOGLU, Mufide DİNCER, Mugem Asli GUREL, Nehir Canıgür BAVBEK

Comparison of results of minimal invasive surgery for pilonidal sinus with Karydakis procedure: less is more

Osman CİVİL, Cagri TİRYAKİ, Mehmet OZYİLDİZ, Murat Burç YAZICIOĞLU, Adem YUKSEL, Selim Yigit YİLDİZ, Murat COSKUN

Multiple cervical spinous process fracture (clay shoveler fracture): Case report

Mustafa OZER, Tacettin AYANOĞLU, Muhammet Baybars ATAOGLU, Mehmet Ali TOKGÖZ, Ahmet YILDIRIM

Prescribers adherence to the basic principles of prescription order writing in shashemene referral hospital and malka oda district hospital

Messay WOLDE-MARİAM, Diriba GEMEDA, Yarlagadda RAGHAVENDRA

Effect of repaglinid on ovariectomy induced bone loss in rats: comparison with 17β-estradiol

Mustafa ULAS

Recovery in a three years old male child after bell’s palsy: A case report

Farjad AFZAL, Sidra MANZOOR, Asma AFZAL