Development of web-based software for acute coronary syndrome and a medical data mining application

Development of web-based software for acute coronary syndrome and a medical data mining application

Aim: Medical data mining is based on data mining methods and related intelligent methods (e.g., granular computing, neural networks and soft computing) used in medicine. In this research, it was aimed to develop a web-based software and to implement medical data mining on the records of the patients with acute coronary syndrome.Materials and Methods: The data in this study included retrospective observations recorded in the database from the webbased software developed for Cardiology Department, Turgut Özal Medical Center, Inonu University. PHP (Personal Home Page) programming language and MySQL Database Management System were employed for the development of the web-based software system. Laplace Support Vector Machines (LSVM) was constructed to predict absence or presence of diabetes mellitus in patients with acute coronary syndrome.Results: A web based software performing data entry, query, delete, update, etc. was developed. As a result of medical data mining application, the accuracy and area under ROC curve with 95% CI were obtained as; 0.9804 (0.9716 - 0.987) and 0.9332 (0.9096 -0.9567), respectively.Conclusion: The developed web-based software created a very important infrastructure for implementing medical data mining applications. It was determined that the LSVM model produced very good predictive results to estimate absence or presence of diabetes mellitus in patients with acute coronary syndrome.

___

  • Wannamethee SG, Shaper AG, Perry IJ, Smoking as a modifiable risk factor for type 2 diabetes in middle-aged men. Diabetes Care 2001;24(9):1590-5.
  • Baptiste-Roberts K, Barone BB, Gary TL, Golden SH, Wilson LM, Bass EB, et al. Risk factors for type 2 diabetes among women with gestational diabetes: a systematic review. Am J Med 2009;122(3):207-14.
  • Rich-Edwards JW, Colditz GA, Stampfer MJ, Willett WC, Gillman MW, Hennekens CH, et al. Birthweight and the risk for type 2 diabetes mellitus in adult women. Ann Intern Med 1999;130(4 Pt 1):278-84.
  • Kempf K, Herder C, Erlund I, Kolb H, Martin S, Carstensen M, et al. Effects of coffee consumption on subclinical inflammation and other risk factors for type 2 diabetes: a clinical trial. Am J Clin Nutr 2010;91(4):950-7.
  • Bonora E, Kiechl S, Willeit J, Oberhollenzer F, Egger G, Meigs JB, et al. Population-based incidence rates and risk factors for type 2 diabetes in white individuals: the Bruneck study. Diabetes 2004;53(7):1782-9.
  • Gress TW, Nieto FJ, Shahar E, Wofford MR, Brancati FL. Hypertension and antihypertensive therapy as risk factors for type 2 diabetes mellitus. Atherosclerosis Risk in Communities Study. N Engl J Med 2000;342(13):905-12.
  • White WB, Cannon CP, Heller SR, Nissen SE, Bergenstal RM, Bakris GL, et al. Alogliptin after Acute coronary syndrome in patients with type 2 diabetes. N Engl J Med 2013;369(14):1327-35.
  • Çolak MC, Çolak C, Kocatürk H, Sağıroğlu Ş, Barutçu İ. Predicting coronary artery disease using different artificial neural network models. Anadolu Kardiyol Derg 2008;8(4):249-54.
  • Targher G, Bertolini L, Poli F, Rodella S, Scala L, Tessari R, et al. Nonalcoholic fatty liver disease and risk of future cardiovascular events among type 2 diabetic patients. Diabetes 2005;54(12):3541-6.
  • Gong C, Xing J, Hu Y. Data communication of Android mobile terminal and PHP and MySQL based on JSON [J]. Industrial Instrumentation Automation 2013;1:021.
  • Aslan E, Durmaz F. Rehabilitasyon Amaçlı Bilgisayar Veri Tabani Yardımıyla Bölgesel Engelli Kişi Haritasının Oluşturulması. CBÜ Soma Meslek Yüksekokulu Teknik Bilimler Dergisi 2011;1(15):64-73.
  • Veikkolainen T, Pesonen LJ, Evans DA. PALEOMAGIA: A PHP/ MYSQL database of the Precambrian paleomagnetic data. Studia Geophysica et Geodaetica. 2014;1;58(3):425-41.
  • Çaycı Ö. PHP ve MySQL. 2.baskı. Seçkin Yayıncılık, Ankara, 2003;368-9.
  • Cortes C, Vapnik V. Support-vector networks. Machine learning 1995;20(3):273-97.
  • Breunig MM, Kriegel H-P, Ng RT, Sander J, editors. LOF: identifying density-based local outliers. ACM Sigmod Record 2000;29(2):93-104.
  • Sümbüloğlu V, Sümbüloğlu K. Klinik saha araştırmalarında örnekleme yöntemleri ve örneklem büyüklüğü. 1.baskı. Hatiboğlu Yayınları, Ankara, 2005;134-5.
  • Alpar R. Uygulamalı istatistik ve geçerlik-güvenirlik: spor, sağlık ve eğitim bilimlerinden örneklerle. 4. baskı. Detay Yayıncılık, Ankara, 2016;412-3.
  • Minitab I. MINITAB statistical software. Minitab Release. 2015;16.
  • Soni J, Ansari U, Sharma D, Soni S. Predictive data mining for medical diagnosis: An overview of heart disease prediction IJCA 2011;17(8):43-8.
  • Cios KJ, Moore GW. Uniqueness of medical data mining. Artif intell Med 2002;26(1-2):1-24.
  • Colak C, Karaman E, Turtay MG. Application of knowledge discovery process on the prediction of stroke. Comput Methods Programs Biomed 2015;119(3):181-5
  • Koyuncugil AS, Özgülbaş N. Veri Madenciliği: Tıp ve Sağlık Hizmetlerinde Kullanımı ve Uygulamaları. IJIT 2009;2(2):21-32.
  • Organization WH. Global report on diabetes. World Health Organization, France, 2016.
  • Grech ED, Ramsdale DR. Acute coronary syndrome: unstable angina and non-ST segment elevation myocardial infarction. BMJ. 2003;326(7401):1259-61.
  • Amsterdam EA, Wenger NK, Brindis RG, Casey Jr DE, Ganiats TG, Holmes Jr DR, et al. 2014 AHA/ACC guideline for the management of patients with non-ST-elevation acute coronary syndromes: executive summary: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines. Circulation. 2014;130(25):2354-94.
İnönü Üniversitesi Turgut Özal Tıp Merkezi Dergisi-Cover
  • ISSN: 1300-1744
  • Yayın Aralığı: Yılda 4 Sayı
  • Yayıncı: İnönü Üniversitesi Tıp Fakültesi