İlke Mungan AKIN, Cengiz YAKINCI, Yılmaz TABEL, Özgü Suna CELİLOĞLU

Yenidoğanda akut böbrek yetmezliği ve akut periton diyalizi uygulamaları

Akut böbrek yetmezliği (ABY), yenidoğan yoğun bakım ve prematüre yoğun bakım kliniklerinde sık görülen, tedavisi ve izlemi zor, sonuçları ile pek yüz güldürücü olmayan bir hastalıktır. ABY’nin tanı, tedavi ve izleminde en önemli nokta prerenal ve postrenal ABY’nin erken tanınması ve yoğun tedavisi ile prognozu daha kötü olan intrensek ABY’nin önlenmesidir. Biz bu yazımızda; yenidoğan yoğun bakım ünitemizde son 6 ayda yaptığımız akut periton diyalizi uygulamalarımızı da derleyerek bu konuyu geniş bir şekilde incelemeyi ve sunmayı amaçladık.

Acute renal failure in neonates and practice of acute peritoneal dialysis

Acute renal failure (ARF), very frequently observed in neonatal intensive care units, is a disease which is hard to treat, follow and which does not have good end results. The most important point in diagnosis, treatment and follow-up of ARF is the early differentiation of prerenal type from post-renal ARF and avoidance of intrinsic type ARF with intensive treatment. In this manuscript; we aimed to discuss this subject in detail, with our peritoneal dialysis experience in our neonatal intensive care unit during the last 6 months.

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1. Siegel NJ, Van Why SK, Devarajan P. Pathogenesis of acute renal failure. In: Avner ED, Harmon WE, Niaudet P, ed(s): Pediatric Nephrology, 5th ed. Philadelphia:Lippincott Williams&Wilkins 2004;1223-32.
2. Fitzpatrick MM, Kerr SJ, Bradbury MG. The child with acute renal failure. In:Webb NJA, Postlethwaite RJ, ed(s): Clinical Paediatric Nephrology, 3rd ed. New York: Oxford University Press 2003;405-25.
3. Nissenson AR. Acute renal failure: Definition and pathogenesis. Kidney Int Suppl 1998;53:7–10.
4. Gouyan JB, Guignard JP. Management of acute renal failure in newborns. Pediatr Nephrol 2000;14:1037–44.
5. Demircin G. Yenidoğanda böbrek fonksiyonları ve böbrek yetmezliği. Türkiye Klinikleri Pediatrik Nefroloji özel sayısı. 2004;2:96–103.
6. Corey HE, Spitzer A. Renal blood flow and glomerular filtration rate during development. In: Edelmann CM, ed. Pediatric Kidney Disease. Boston:Little, Brown and Company 1992:49–77.
7. Blackburn ST, Loper DL. The renal system and fluid and electroyte homeostasis. In: Blackburn ST, Loper DL, ed(s). Maternal, Fetal and Neonatal Physiology.Mexico: WB. Saunders Company 1992:336–78.
8. Guignard JP. Renal morphogenesis and development of renal function. In: Taeusch HW, Ballard RA, ed(s). Avery’s Diseases of the Newborn. Philadelphia: WB. Saunders Company 1998:1123–30.
9. Robillard JE, Smith FG. Developmental aspects of renal function during fetal life. In: Edelmann CM, ed. Pediatric Kidney Disease. Boston: Little, Brown and Company 1992:3–18.
10. Kher KK. Neonatal renal function. In: Kher KK, Makker SP, ed(s). Clinical Pediatric Nephrology. Singapore: Mc-Graw Hill, Inc 1992:727–43.
11. Awad H, El-Safty I, El-Barbary M, Imam S. Evaluation of renal glomerular and tubular functional and structural integrity in neonates. Am J Med Sci 2002;324:261–6.
12. Cuzzolin L, Dal Cere M, Fanos V. NSAID-induced nephrotoxicity from the fetus to the child. Drug Saf 2001;24(1):9–18.
13. Akima S, Kent A, Reynolds GJ, Gallagher M, Falk MC. Indomethacin and renal impairment in neonates. Pediatr Nephrol 2004;19(5):490–3.
14. Gallini F, Maggio L, Romagnoli C, Marrocco G, Tortorolo G. Progression of renal function in preterm neonates with gestational age ≤32 weeks. Pediatr Nephrol 2000;15:119–24.
15. Bauer R, Walter B, Ihring W, Kluge H, Lampe V, Zwiener U. Altered renal function in growth-restricted newborn piglets. Pediatric Nephrol 2000;14:735–9.
16. Guignard JP, Drukker A. Clinical neonatal nephrology. In: Barratt TM, Avner ED, Harmon WE, ed(s). Pediatric Nephrology, 4th ed. Pennsylvania: Lippincott Williams& Wilkins 1999:1051–66.
17. Clark DA. Times of first void and first stool in 500 newborns. Pediatrics 1977;60:457–9.
18. Kleinman LI, Steward CL, Kaskel FJ. Renal disease in the newborn. In: Edelmann CM, ed. Pediatric Kidney Disease. Boston: Little, Brown and Company 1992:1043–66.
19. Norman ME, Asadi FK. A prospective study of acute renal failure in the newborn infant. Pediatrics 1979;63:475–9.
20. Kher KK. Neonatal disorders. In: Kher KK, Makker SP, ed(s). Clinical Pediatric Nephrology. Singapore: Mc-Graw Hill, Inc 1992:745–71.
21. Toth-Heyn P, Drukker A, Guignard JP. The stressed neonatal kidney: from pathophysiology to clinical management of neonatal vasomotor nephropathy. Pediatr Nephrol 2000;14:227–39.
22. Pejovic B, Peco-Antic A, Dunjic R. Acute oliguric renal failure in hypoxic neonates born at full term. Srp Arh Celok Lek 2002;130(11–12):367–70.
23. Mathur NB, Agarwal HS, Maria A. Acute renal failure in neonatal sepsis. Indian J Pediatr 2006;73(6):499–502.
24. Morelli S, Ricci Z, Di Chiara L, et al. Renal replacement therapy in neonates with congenital heart disease. Contrib Nephrol 2007;156:428–33.
25. Seri I, Evans J, Tulassay T. Renal insufficiency and acute renal failure. In: Taeusch HW, Ballard RA, ed(s). Avery’s Diseases of the Newborn. Philadelphia: WB. Saunders Company 1998:1158–64.
26. Streitman K, Toth A, Horvath I, Talosi G. Renal injury in perinatal hypoxia: ultrasonography and changes in renal function. Eur J Pediatr 2001;160:473–7.
27. Mattyus I, Zimmerhackl LB, Schwarz A, Brandis M, Miltenyi M, Tulassay T. Renal excretion of endothelin in children. Pediatr Nephrol 1997;11:513–21.
28. Scott RJ, Rochefort M. Fatal perinatal nephropathy with onset in intrauterin life. Arch Dis Child 1992;67:1212–3.
29. Merlob P, Litwin A, Lazar L, Zaizov R. Neonatal ABO incompatibility complicated by hemoglobinuria and acute renal failure. Clin Pediatr 1990;29:219–22.