E-commerce is a new way of shopping through using internet since 1990s. This latest from of shopping is based on progress in information technologies. In the 1990s, companies just as Amazon and eBay started to change the shopping behavior of people. In this research, e-commerce index of 44 Sub-Saharan African countries are calculated by using World Development Indicators which are issued by the World Bank Group. The E-commerce index is consisting of access to electricity, cost of business start-up procedures, fixed broadband subscriptions, internet users, mobile cellular subscriptions and secure Internet servers. It is assumed that this combined index shows the readiness of countries for international e-commerce and they are compared with Human Development Index (HDI) to identify a correlation between them. The result shows that there is a moderate positive correlation between e-commerce index and HDI.