Duygu ONUR CURA, Tufan ÇANKAYA, Ayfer ULGENALP

Cinsiyet Disforisinde Genetik Faktörlerin Rolü

Bireylerin mevcut biyolojik cinsiyetlerinden hoşnutsuzlukları ve karşıt cinsiyete ait hissetme durumu cinsiyet disforisi olarak tanımlanır. Bu davranış özelliğinin oluşmasında çevresel birçok faktörün yanı sıra kişilerin kendine has genetik özellikleri de etkilidir. Kişilerin yaşamında köklü değişikliklere neden olan bu durumun genetik temelini araştıran çalışmalar nispeten yenidir. Bu derlemede, cinsiyet disforisi olan bireylerde bu davranış paterninin genetik temelini araştıran çalışmalar irdelenmiş ve gelecek araştırmalar için yol gösterici olacak bilgilere yer verilmiştir.

Anahtar Kelimeler:

Cinsiyet disforisi, epigenetik çalışmalar, moleküler genetik çalışmalar, sitogenetik çalışmalar

The Role of Genetic Factors in Gender Dysphoria

The dissatisfaction of individuals with their existing biological sex and feeling of belonging to the opposite sex is defined as gender dysphoria. Many environmental factors and genetic features are effective in the emergence of this behavior. Studies investigating the genetic basis of this condition, which leads to serious changes in people's lives, are relatively new. In this review, the studies investigating the genetic basis of this behavioral pattern in individuals with gender dysphoria are examined and information that will guide for future researches is presented.

Keywords:

Cytogenetic studies, epigenetic studies, gender dysphoria, molecular genetic studies,

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