Coşkun ŞİMŞİR, Ziya KALEM, Batuhan BAKIRARAR, Muberra NAMLI KALEM

Spontan ve invitro fertilizasyon ikiz gebeliklerinde gebeliğe ait ve neonatal verilerin karşılaştırılması

Amaç: Bu çalışmanın amacı invitro fertizasyon(IVF) tedavisi ile gerçekleşen ikiz gebelikler ilespontan gerçekleşen ikiz gebeliklerin gebelik ve perinatal dönem bulguları açısındankarşılaştırılmasıdır.Materyal ve Method: Bu çalışma, 2015-2018 yılları arasında, canlı doğumu gerçekleşen dikoryonikdiamniotik ikiz gebeliklerin verileri incelenerek gerçekleştirilmiş bir retrospektif kohort çalışmasıdır.Bu araştırmada gebeliği spontan olarak gerçekleşmiş ikiz gebelikler grubu ve yardımcı üremeteknikleri kullanılarak gebe kalmış IVF ikiz grubu olmak üzere iki çalışma grubu vardırBulgular: Gebeliğe ve doğuma ait problemler her iki grup arasında farklılık göstermemiştir. IVF ikizgebeliklerinde prematurite, düşük doğum ağırlığı ve 1. Dakika APGAR skor düşüklüğü oranlarınındaha fazla olduğu görülmüştür. Perinatal mortalite oranları her iki grupta benzer bulunmuştur.Sonuç: Bu çalışmada gösterilmiştir ki; ikiz gebeliklerde tek gebeliklere göre zaten daha yüksekriske sahip olan erken doğum ve düşük doğum ağırlığı riskleri, IVF ikiz gebeliklerinde daha da fazlaartmaktadır. Bu sonuçlar gözönüne alınarak tek embryo transferine yönelmek ve iatrojenik çoğulgebeliklere destek vermemek önerilmelidir.

Anahtar Kelimeler:

IVF, İkiz gebelikler, tekil gebelikler, neonatal sonuçlar

Comparison of pregnancy and neonatal outcome in spontaneous and invitro fertilization (IVF) twin pregnancies

Background: This study aimed to investigate whether the differences between twininvitrofertilization (IVF) and twin spontaneous pregnancies in terms of pregnancy and perinataloutcome.Material and Methods: This is a retrospective cohort study carried out by examining the data ofdichorionic-diamniotic twin pregnancies with live births in a private hospital between 2015 and 2018.There were two study groups which were the twin pregnancy group with spontaneous pregnancyand the IVF twin group with pregnancy via assisted reproductive techniques.Results: Pregnancy and birth problems did not differ between the two groups. The IVF twinpregnancies were observed to have higher rates of preterm birth, low birthweight and APGAR 1stminute scores. Perinatal mortality rates were found similar in both groups.Conclusion: In conclusion, it was shown in this study that the risks of preterm birth and lowbirthweight which are already higher in twin pregnancies than in singleton pregnancies were evenhigher in the IVF twin pregnancies. It is recommended in accordance with these results that singleembryo transfers should be preferred and iatrogenic multiple pregnancies should not beencouraged.

Keywords:

Twin pregnancies, single pregnancies, IVF, neonatal outcome,

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