Betül TAŞDELEN, Olgun GÜVEN, Bahattin M. BAYSAL

Poli N-izopropilakrilamid/itakonik asit kopolimerik hidrojelleri tarafından sulu çözeltilerde vitamin B12 adsorpsiyonu

Farklı miktarda itakonik asit içereb N-izopropilakrilamid/itakonik asit kopolimerik hidrojelleri NIPAAm/IA g-radyasyonu ile sentezlendi. Sentezlenen hidrojeller Vitamin B12 tutulumu ve salımını incelemekte kullanıldı. Vitamin B12 adsorpsiyon deneylerinde S tipi adsorpsiyon izotermi bulundu. Hidrojellerin ilaç tutulumu ve salımı davranışları üzerinde komonomer konsantrasyonu ve ışınlama dozunun etkileri araştırıldı.

Anahtar Kelimeler:

Hidrojel, N-izopropilakrilamid, itakonik asit, Vitamin B12

Adsorption of vitamin B12 in aqueous solutions by poly N-isopropylacrylamide/ itaconic acid copolymeric hydrogels

N-isopropylacrylamide/itaconic acid copolymeric hydrogels NIPAAm/IA containing different quantities of itaconic acid have been irradiated with g radiation. The hydrogels were used in an experiment concerning the uptake and release behavior of Vitamin B12. In the experiment of the adsorption of Vitamin B12, type S ad- sorption isotherm was found. The effect of comonomer concentration and irradiation dose on the uptake and release behavior of the hydrogels was studied.

Keywords:

Hydrogel, N-isopropylacrylamide, itaconic acid, Vitamin B12,

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