Aralıklı Antrenman Programının Kadınlarda NFE2L2/Nrf2 Gen İfadesine Etkisi

Aralıklı antrenman programının bayanlarda Nuclear factor erythroid-derived 2-like 2 (NFE2L2/Nrf2) gen ekspresyonuna etkisinin olup olmadığını araştırmaktır. Araştırma 12 kadın üzerinde yapıldı. Katılımcılara, haftada 3 gün olmak üzere 8 hafta süreyle orta süreli interval antrenman programı uygulandı. 8 haftalık antrenmanlar öncesi ve sonrası kan örnekleri alındı. Periferik kan mononükleer hücrelerinden TRIzol Reaktifi kullanılarak RNA izolasyonu yapıldı. NFE2L2 gen ekspresyonu Biomark Real-Time PCR (RT-PCR) ile belirlenmiştir. Çalışmaya katılan katılımcıların maksimal oksijen kullanma kapasitesinde (VO2 Max) egzersiz sonrası önemli ölçüde artış bulundu (p

The Effect of Interval Training Program on Nuclear Factor Erythroid-Derived 2-like 2 (NFE2L2/Nrf2) Gene Expression in Women

Purpose in this work, to investigate whether interval training program has an effect on Nuclear factor erythroid-derived2-like 2 (NFE2L2/Nrf2) gene expression in women.The research was made on 12 women. Participants were given amedium-term interval training program for 8 weeks, 3 days a week. The blood samples of the participants were collected before and after the 8 weeks of training. RNA isolation was performed using TRIzol Reagent from peripheral bloodmononuclear cells. NFE2L2 gene expression was determined by Biomark Real-Time PCR (RT-PCR). The participants was asignificant increase in heart rate and maximal oxygen use capacity (VO2 max ) after the exercise (p

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