DNAJC25 as a tumor suppressor candidate gene in breast cancer
DNAJC25 gene is a member of the HSP40 (DNAJ) family, and it was suggested as a tumor suppressor gene in hepatocellular carcinoma. The aim of this study was to analyze the expression, genetic/epigenetic alterations, and prognostic value of the DNAJC25 gene in breast cancer. DNAJC25 transcript levels are upregulated in BT-20 and ZR-75-1 cell lines and downregulated in MDA-MB-231 cell line compared to the non-tumorigenic mammary epithelial cell line (MCF 10A) (P
Keywords:
DNAJC25, HSP40, biomarker breast cancer,
___
- Reference1 Prof. Dr. Uygar Halis TAZEBAY (tazebay@gtu.edu.tr ) Reference2 Prof. Dr. K. Can AKÇALI (can.akcali@ankara.edu.tr )
- ISSN: 2687-475X
- Yayın Aralığı: Yılda 4 Sayı
- Başlangıç: 1972
- Yayıncı: Hacettepe Üniversitesi, Fen Fakültesi
Sayıdaki Diğer Makaleler
Uromyces euphorbiae Cooke & Peck, A New Rust Fungi (Pucciniales) Record for Turkey
Şanlı KABAKTEPE, Birol MUTLU, Şükrü KARAKUŞ
Sevda KIRBAĞ, Gülben TORĞUT, Pınar ERECEVİT SÖNMEZ, Güzin PIHTILI
Şanlı KABAKTEPE, Birol MUTLU, Şükrü KARAKUŞ
Gönül DÖNMEZ, Nur KOÇBERBER KILIÇ
Münevver AKSOY, Tammy T. LA, Nuenyan LAM, Charlene L. FOREST
Dürdane YILMAZ, Dila KAYA, Kaan KEÇECİ, Ali DİNLER
Murat ÇANKAYA, Ayşe Hümeyra TAŞKIN KAFA, Mehmet KUZUCU, Arzu ÇÖLERİ CİHAN