Yaşlılarda Hiponatremiyle İlişkili Faktörler

Amaç: Hiponatremi yaşlı hastalarda en sık görülen elektrolit bozukluğudur, kötü prognoz ve mortalite artışı ile ilişkilidir. Bu çalışmanın amacı, yaşlı erişkinlerde hiponatremi ile ilişkili komorbid hastalıkları ve ilaçları incelemektir. Gereç ve Yöntemler: Bu retrospektif, kesitsel bir çalışmada geriatri kliniğine başvuran 240 yaşlı hasta (yatarak ve ayakta tedavi gören hasta) değerlendirdi. Tüm katılımcıların demografik özellikleri, komorbiditeleri, ilaçları ve laboratuvar bulguları değerlendirildi. Hiponatremi, sodyum düzeyi <135 mmol / L olarak tanımlandı. Bulgular: Çalışmada hiponatremi prevalansı % 22.1 idi ve ortalama yaş 75.27 ± 7.28 olarak saptandı. Hiponatremi grubunda hipertansiyon (HT), diabetes mellitus (DM), konjestif kalp yetmezliği (KKY), aterosklerotik kalp hastalığı (ASKH) sıklığı daha yüksekti (p<0.05). Diüretik, antidepresan ve antipsikotik ilaç kullanım sıklığı hiponatremi grubunda daha fazla olarak tespit edildi (p< 0.05). Sonuç: Bazı komorbiditeler ile diüretik, antidepresan ve antipsikotik gibi yaşlılarda sık reçete edilen ilaç gruplarının hiponatremi ile ilişkili olabileceği gösterilmiştir. Bu açıdan geriatri pratiğinde hastaları değerlendirmek önemlidir.

Anahtar Kelimeler:

hiponatremi, yaşlılık, diüretik, komorbidite

The Factors Associated Hyponatremia in Older Adults

Aim: Hyponatremia is the most common electrolyte disturbance in older adults and is associated with poor prognosis and increased mortality. The aim of this study was to investigate comorbid diseases and drugs associated with hyponatremia in older adults. Material and Methods: In this retrospective and cross-sectional study, 240 elderly patients (inpatients and outpatients) admitted to the geriatrics clinic were evaluated. Demographic characteristics, comorbidities, drugs and laboratory findings of all participants were evaluated. Hyponatremia was defined as sodium level <135 mmol / L. Results: The prevalence of hyponatremia was 22.1% and the mean age was 75.27 ± 7.28 years. The frequency of hypertension (HT), diabetes mellitus (DM), congestive heart failure (CHF), and atherosclerotic heart disease (ASHD) were higher in the hyponatremia group than normonatremia group (p <0.05). The incidence of diuretics, anridepressant and antipsychotic drugs usage was higher in hyponatremia group (p <0.05). Conclusions: Several comorbidities and frequently prescribed drug groups in older adults such as diuretics, antidepressants and antipsychotic medicines may be associated with hyponatremia. In this respect, it is necessary to evaluate patients in geriatric practice in terms of comorbidities and drugs.

Keywords:

hyponatremia, old age, diuretic, comorbidity,

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Yayın Aralığı: Yılda 3 Sayı
Başlangıç: 2018
Yayıncı: Geriatrik Bilimler Derneği

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