Herpes Zoster Hastalarının Demografik ve Klinik Özelliklerinin Değerlendirilmesi

Özet Amaç: Herpes zoster 50 yaş üzerinde daha sık görülen ve post herpetik nevralji gelişmesi nedeniyle yaşam kalitesini etkileyen bir hastalıktır. Bu çalışmada herpes zoster tanısı almış hastaların demografik ve klinik özelliklerinin incelenmesi amaçlanmıştır. Yöntem:: Bu kesitsel çalışmada dermatoloji bölümünde 2013-2020 yılları arasında herpes zoster tanısı ile izlenen hastaların verileri geriye dönük olarak incelendi. Bulgular: 440 hastanın 252’si (%57,3) kadın, 188’i (%42,7) erkekti. Yaş ortalaması 48,9±18 yıl (4- 94 yıl) idi. En sık yerleşim bölgesi %35,5 oranında torakal bölge ve ikinci sırada %21,4 oranında lomber bölgeydi. Dissemine tutulum ve oftalmik zona ileri yaştaki hastalarda daha sık görüldü (p<0,001). Komorbiditeler arasında en sık saptananlar %12,6 oranı ile hipertansiyon ve koroner arter hastalığı birlikteliği, %10,3 ile kanser, %5,9 diyabet ve hipertansiyon birlikteliğiydi. Şiddetli ağrı hastaların %19.7’sinde izlendi ve kadınlarda daha sıktı (p=0.016). HT+KAH grubunda ve kanser hastalarında orta ve şiddetli ağrı oranı yüksekti (p˂0.001). 50 yaş üzerindeki hastaların %15,3’ ünde post herpetik nevralji izlendi. Sonuç: Herpes zoster özellikle yetişkinlerde sıklıkla görülmektedir. Akut ağrı oluşturması ve postherpetik nevralji gelişebilmesi nedeniyle, özellikle riskli hasta gruplarının takip ve tedavisine önem gösterilmesi gerekmektedir.

Anahtar Kelimeler:

herpes zoster, klinik özellikler, postherpetik nevralji

Evaluation of the Demographic and Clinical Characteristics of Patients Diagnosed with Herpes Zoster

Background: Herpes zoster is a disease that is more frequently seen in people aged over 50 years and negatively affects the quality of life due to the development of post-herpetic neuralgia. This study aimed to investigate the demographic and clinical characteristics of patients diagnosed with herpes zoster. Methods: In this cross-sectional study, the data of patients who were followed up with a diagnosis of herpes zoster at the dermatology department between 2013 and 2020 were retrospectively examined. Results: Of 440 patients, 252 (57.3%) were female and 188 (42.7%) were male. The mean age was 48.9±18 (4-94) years. The most common localization was the thoracic region at a rate of 35.5% and the lumbar region at a rate of 21.4%. Disseminated and ophthalmic zoster were more common in elderly patients (p<0.001). The most common comorbidities were hypertension (HT)+coronary artery disease (CAD) (12.6%), cancer (10.3%), and diabetes+HT (5.9%). Severe pain was observed in 19.7% of the patients and was more common in women (p=0.016). The rate of moderate and severe pain was high in the patients with HT+CAD and cancer (p˂0.001). Post-herpetic neuralgia was observed in 15.3% of the patients aged over 50. Conclusions: Herpes zoster is especially common in adults. Since it causes acute pain and can lead to postherpetic neuralgia development, risky patient groups should be more carefully followed up and treated.

Keywords:

herpes zoster, clinical features, postherpetic neuralgia,

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