Bilge ASLAN, Feray AYDIN

8112

Adneksiyel Kitle Operasyonlarında İntraoperatif Lidokain'in Kusmayı Önlemesi

Amaç: Postoperatif kusma POK , batın içi operasyonlarda sık görülen bir komplikasyondur. Karın ameliyatı geçiren erişkin hastalarda intravenöz lidokain infüzyonu kullanımı POK'yi önleyebilir. Karın içi operasyonlarda genel anesteziye yardımcı olarak kullanılan intravenöz lidokain infüzyonunun anti-emetik etkisini değerlendirmeyi amaçladık.Hastalar: Elektif olarak adneksiyel kitleden opere olan, 30-70 yaşları arasında, ASA I-III erişkin kadınlar seçildi. Müdahale: Anestezinin indüksiyonunu ve idamesini genel olarak onkolojik cerrahi odalarımızda standart hale getirilmiştir. Hastalara rastgele olarak 5 dakika boyunca lidokain 1.5 mg/kg intravenöz lidokain, ardından 2 mg/kgsaat veya sadece % 0.9 saline aynı oranda ve hacimde verildi. İnfüzyonlar ameliyatın sonuna kadar devam edilmiştir.Bulgular: 200 tane adneksiyel kitleden opere olan bayan hasta tarandı. Lidokain grubunda, 100 hastanın 60'ında % 60 Saline grubunda 100 hastanın 80'inde % 80 POK görüldü. POK sahibi olma olasılığı, Lidokain alan hastalarda Salin verilen gruba göre% 20 daha az bulundu. Ortalama lidokain plazma konsantrasyonu 4.3 µg/ml idi 0.87 - 4.88 .Sonuç: Genel anesteziye yardımcı olarak intravenöz lidokain infüzyonunun kullanılması, elektif adneksiyel kitle operasyonu uygulanan onkoloji hastalarında POBK’yu Postoperatif Bulantı Kusma azaltmıştır
Anahtar Kelimeler:

Genel anestezi, kusma, bulantı, lidokain

Intraoperative lidocaine prevention of vomiting in adnexal mass operations

Objective: Postoperative vomiting POV is a common complication in intra-abdominal operations. The use of intravenous lidocaine infusion in adult patients who underwent abdominal surgery may prevent POV. We aimed to evaluate the anti-emetic effect of intravenous lidocaine infusion used as an adjuvan to general anesthesia in intra-abdominal operations.Patients: ASA I-III adult women aged 30 to 70 years scheduled for elective adnexal mass operations were selected. Intervention: We have standardized the induction and maintenance of anesthesia in our oncological surgery rooms. Patients were randomly administered lidocaine 1.5 mg/kg intravenous i.v lidocaine followed by 2 mg/kg/h or only 0.9% saline same proportion and volume for 5 minutes. Infusions were continued until the end of the surgery.Results: 200 women with adnexal mass were operated. In the lidocaine group, 60 60% of the 100 patients had POV and 80 80% of the 100 patients had POV in the Saline group. The probability of having POV was 20% less in patients receiving lidocaine than in the Saline group. The mean lidocaine plasma concentration was 4.3 µg/ml range: 0.87 to 4.88 . Conclusion: The use of intravenous lidocaine infusion as an adjunct to general anesthesia reduced POVN in oncology patients undergoing elective adnexal mass surgery
Keywords:

General anesthesia, vomiting, nausea, lidocaine,

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Genel Tıp Dergisi-Cover
  • ISSN: 2602-3741
  • Yayın Aralığı: Yılda 6 Sayı
  • Başlangıç: 1997
  • Yayıncı: SELÇUK ÜNİVERSİTESİ > TIP FAKÜLTESİ
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