2023

Rowell Sendromu: Bir Olgu Sunumu ve Literatürün Gözden Geçirilmesi

Rowell sendromu; (RS) lupus eritematozus (LE), eritema multiforme (EM) benzeri lezyonlar ve karakteristik immünolojik bulgularla nadir görülen bir klinik antitedir. Bu durum ilk olarak Rowell ve arkadaşları tarafından 1963 yılında diskoid lupus eritematosuslu (DLE) hastalarda tanımlanmıştır. 2000 yılında Zeitouni ve arkadaşları tarafından RS tanı kriterleri oluşturulmuştur. Majör kriterler; lupus eritematozus varlığı (sistemik, subakut veya diskoid), EM benzeri lezyonlar ve antinükleer antikor (ANA) benekli paterni; minör kriterler ise perniyo, anti-Ro ve/veya anti-La pozitifliği ve romatoid faktör (RF) pozitifliğidir. 3 majör ve 1 minor kriter pozitifliği RS tanısı koydurmaktadır. Bu bildiride EM benzeri lezyonlarla başvuran ve RS tanısı alan 50 yaşında bir kadın hasta sunulmaktadır

Rowell Sendromu: A Case Report and Review of the Literature

Rowell's syndrome (RS) is a rare entity consisting of lupus erythematosus with associated erythema multiforme (EM) like lesions and chacteristic immunological findings. The condition was first described in 1963 by Rowell et al. in patients with discoid lupus erythematosus (DLE). In 2000 Zeitouni et al. redefined the diagnostic criteria for RS. Major criteria are; lupus erythematosus (systemic, subacute or discoid), EM like lesions and antinuclear antibodies (ANA) speckled pattern; minor criteria are; pernio, antiRo and/or anti-La positivity and rheumatoid factor (RF) positivity. 3 major and 1 minor criteria positivity makes the diagnosis of RS. In this report we present a case of 50-year-old female presented with EM like lesions and diagnosed as RS.

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