Preterm Bir Bebekte Non-İnvaziv Solunum Desteği Altında Gelişen ve Spontan Düzelen Pulmoner İnterstisyel Amfizem

Pulmoner interstisyel amfizem (PIA) alveoler ve küçük hava yollarının rüptürü sonucu havanın perivasküler bağ dokusu içinde birikmesi ve interstisyumda toplanması olarak tanımlanan hava kaçağı sendromudur. Sıklıkla yenidoğan döneminde, özellikle mekanik ventilasyon desteği altında izlenen prematüre bebeklerde görülür. Burada invaziv mekanik ventilasyon desteği almamasına rağmen akciğer grafisinde kistik, kaviter görünüm saptanan ve konservatif tedavi ile düzelen lokalize PİA tanısı alan bir prematüre hasta sunulmuştur.

Spontaneous Resolution of Pulmonary Interstitial Emphysema in A Preterm Infant on Non-Invasive Mechanical Ventilation

Pulmonary interstitial emphysema (PIA) is an air leak syndrome defined as the accumulation of air in the perivascular connective tissue and collection in the interstitium as a result of rupture of the alveolar and small airways. It is frequently seen in the neonatal period, especially in premature babies followed up under mechanical ventilation support. Here, a premature patient who received no invasive mechanical ventilation support and was diagnosed with localized PIA that recovered with conservative treatment is presented.

PDF

___

1. Gross I. Pulmonary air leaks. In: McMillan JA, DeAngelis CD, Feigin RD, Warshaw JB, eds. Oski's Pediatrics. Philadelphia. Lippincott Williams&Wilkins 1999; 260-262.
2. Whisett JA, Rice WR, Warner BB, Wert SE, Pryhuber GS. Acute Respiratory Disorders. In: MacDonald MG, Mullett MD, Seshia MMK, eds. Avery's Neonatology. 6th ed. Philadelphia. Lippincott Willliams& Wilkins 2005; 553-77.
3. Ovalı F. Hava kaçağı sendromları. In: Dağoğlu T, ed. Neonatoloji: Nobel Tıp Kitabevleri 2000.
4. Elemen L, Baslo GG, Bafi EK, ÖZ F, Erdoğan E. Yenidoğanda ender bir solunum sıkıntısı nedeni: Konjenital lober amfizem ve pulmoner interstisyel amfizem birlikteliği. Çocuk Dergisi 2008; 8: 120- 3.
5. Matta R, Matta J, Hage P, Nassif Y, Mansour N, Diab N. Diffusepersis- tent interstitial pulmonary emphysema treated by lobectomy. Ann Thorac Surg 2011; 92: 73-5.
6. Goldberg RN, Abdenour GE. Air leak syndrome. In: Spitzer AR, ed. Intensive Care of the Fetus and Neonate. St. Louis: Mosby 1996; 629-40.
7. Verma RP, Chandra S, Niwas R, Komaroff E. Risk factors and clinical outcomes of pulmonary interstitial emphysema in extremely low birth weight infants. J Perinatol 2006; 26: 197-200.
8. Miller MJ, Fanarof AA, Martin RJ. Respiratory disorders inpreterm and terminfants. In: Fanaroff AA, Martin RJ, eds. Neonatal Perinatal Medicine Diseases of the Fetus and Infant. 9th ed. St. Louis. Mosby 2011: 1164-88.
9. McMillan JA, DeAngelis CD, Feigin RD, Warshaw JB. Gross I. Pulmonary air leaks, Oski’s Pediatrics. Philadelphia. Lippincott Williams&Wilkins 1999;260-262.
10. Berk DR, Varich LJ. Localized persistent pulmonary interstitial emphysema in a preterm infant in the absence of mechanical ventilation. Pediatr Radiol 2005; 35: 1243-5.