Demet ÇİÇEK, Başak KANDİ, Haydar UÇAK, Bengü ÇOBANOĞLU

Mikozis Fungoides ile Leser-Trelat Birlikteliği Olan Bir Olgu

Leser-Trelat belirtisi malignensilerin neden olduğu aniden artış gösteren çok sayıda seboreik keratoz lezyonlarıyla karakterize nadir görülen bir bulgudur. Çok sayıda değişik internal malignensilerle birlikteliği rapor edilmiştir. Mikozis fungoides (MF) ve Sezary Sendromuyla birlikteliği ise son derece nadirdir. 67 yaşında erkek hasta vücutta kırmızı ve siyah renkli lekelenme şikayeti ile polikliniğimize başvurdu. Gövdedeki eritemli lezyonlardan alınan biopsi materyalinin histopatalojik incelenmesi MF ile uyumlu bulunurken hiperpigmente papül ve plaklara klinik olarak seboreik keratoz tanısı konuldu. Klinik ve histopatolojik bulgularla MF ve leser-trelat birlikteliği tanısı konulan hastaya PUVA tedavisi başlandı. Takip ve tedavisi devam eden hastanın MF ve seboreik keratozla ile uyumlu lezyonları geriledi.©2008, Fırat Üniversitesi, Tıp Fakültesi

Anahtar Kelimeler:

Mikozis fungoides, Leser-Trelat belirtisi

A Leser-Trelat Case Related With Mycosis Fungoides

The sign of Leser-Trelat, a rare finding, is the sudden eruption of multiple seborrhoeic keratoses caused by a malignancy. It was reported to be accompanied by many various internal malignancies. It is rarely accompanied with mycosis fungoides (MF) and Sezary syndrome. A 67-year old male patient applied to our polyclinics with the complaint of red and black spots on his body. Hystopathological examination of the biopsy material taken from the erythematic lesions on the body was found as MF and the hyperpigment papules and plaques clinically were diagnosed as seborrhoeic keratoses. PUVA treatment was initiated on the patient, who was diagnosed as mycosis fungoides and leser-trelat accompaniment based on the clinical and hystopathological findings. The lesions with MF and seborrhoeic keratoses have regressed in the patient, who is still being followed and treated. ©2008, Firat University, Medical Faculty

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